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MX2 Produits

(MX dynamin like GTPase 2 (MX2))

Catégories

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008].

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Catégories MX2 en vedette

MX2 Anticorps

High quality antibodies with extensive validation data.

MX2 Kits ELISA

Reliable ELISA kits for a wide range of species.

MX2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MX2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6259565
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7156645
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN518112
Quantité 50 μg
Fiche technique Fiche technique

MX2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958001
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5657129
Quantité 96 tests
Fiche technique Fiche technique

MX2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311682
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2130696
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409755
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MX2

Kane, Rebensburg, Takata, Zang, Yamashita, Kvaratskhelia, Bieniasz: "Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2." dans: eLife, Vol. 7, (2019) (PubMed).

Martinez-Lopez, Martin-Fernandez, Buta, Kim, Bogunovic, Diaz-Griffero: "SAMHD1 deficient human monocytes autonomously trigger type I interferon." dans: Molecular immunology, Vol. 101, pp. 450-460, (2019) (PubMed).

Yi, An, Liu, Xu, Raniga, Li, Zhou, Wang, Zhang, Zhou, Zhang, An, Qin, Guo, Li, Liang, Cen: "Human MxB Inhibits the Replication of Hepatitis C Virus." dans: Journal of virology, Vol. 93, Issue 1, (2019) (PubMed).

Opp, Vieira, Schulte, Chanda, Diaz-Griffero: "MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells." dans: Journal of virology, Vol. 90, Issue 6, pp. 3056-64, (2016) (PubMed).

Wei, Guo, Ma, Markham, Yu: "Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations." dans: EBioMedicine, Vol. 8, pp. 230-6, (2016) (PubMed).

Sali, Pryke, Abraham, Liu, Archer, Broeckel, Staverosky, Smith, Al-Shammari, Amsler, Sheridan, Nilsen, Streblow, DeFilippis: "Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses." dans: PLoS pathogens, Vol. 11, Issue 12, pp. e1005324, (2015) (PubMed).

Sandler, Bosinger, Estes, Zhu, Tharp, Boritz, Levin, Wijeyesinghe, Makamdop, del Prete, Hill, Timmer, Reiss, Yarden, Darko, Contijoch, Todd, Silvestri, Nason, Norgren, Keele, Rao, Langer, Lifson et al.: "Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. ..." dans: Nature, Vol. 511, Issue 7511, pp. 601-5, (2014) (PubMed).

Kane, Yadav, Bitzegeio, Kutluay, Zang, Wilson, Schoggins, Rice, Yamashita, Hatziioannou, Bieniasz: "MX2 is an interferon-induced inhibitor of HIV-1 infection." dans: Nature, Vol. 502, Issue 7472, pp. 563-6, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à MX2

MX dynamin-like GTPase 2 (Mx2), MX dynamin like GTPase 2 (Mx2), MX dynamin like GTPase 2 (MX2), myxovirus (influenza virus) resistance 2 (mouse) (MX2), AI528743, Mx-2, Mx3, MXB

Protein level used designations for MX2

  • interferon-induced GTP-binding protein Mx2
  • myxovirus resistance protein 2
  • interferon-induced GTP-binding protein Mx3
  • myxovirus (influenza virus) resistance 3
  • myxovirus resistance protein 3
  • interferon-regulated resistance GTP-binding protein MXB
  • p78-related protein
  • second interferon-induced protein p78
  • Mx protein
  • myxovirus (influenza virus) resistance 2 , interferon-inducible protein p78
  • GTP-binding protein Mx2
  • myxovirus resistance 2
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