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MXD3 Produits

(MAX Dimerization Protein 3 (MXD3))

Catégories

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008].

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Catégories MXD3 en vedette

MXD3 Anticorps

High quality antibodies with extensive validation data.

MXD3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MXD3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN949698
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7159074
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (2)
N° du produit ABIN184841
Quantité 100 μg
Fiche technique Fiche technique

MXD3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311688
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3124290
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3083226
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MXD3

Barisone, Satake, Lewis, Duong, Chen, Lam, Nolta, Dίaz: "Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells." dans: Blood cells, molecules & diseases, Vol. 54, Issue 4, pp. 329-35, (2015) (PubMed).

Ngo, Barisone, Lam, D?az: "MXD3 regulation of DAOY cell proliferation dictated by time course of activation." dans: BMC cell biology, Vol. 15, pp. 30, (2014) (PubMed).

Satake, Duong, Chen, Barisone, Diaz, Tuscano, Rocke, Nolta, Nitin: "Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia." dans: British journal of haematology, Vol. 167, Issue 4, pp. 487-99, (2014) (PubMed).

Carneiro, Donnet, Rejtar, Karger, Barisone, Díaz, Kortagere, Lemire, Levin: "Histone deacetylase activity is necessary for left-right patterning during vertebrate development." dans: BMC developmental biology, Vol. 11, pp. 29, (2011) (PubMed).

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." dans: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Hurlin, Quéva, Koskinen, Steingrímsson, Ayer, Copeland, Jenkins, Eisenman: "Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation." dans: The EMBO journal, Vol. 14, Issue 22, pp. 5646-59, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à MXD3

MAX dimerization protein 3 (mxd3), MAX dimerization protein 3 (MXD3), Max dimerization protein 3 (Mxd3), MAX dimerization protein 3 L homeolog (mxd3.L), 4631412E13Rik, BHLHC13, bHLHc13, Mad, Mad3, MAD3, MYX, Myx, zgc:66281

Protein level used designations for MXD3

  • MAX dimerization protein 3
  • Max-associated protein 3
  • Max-interacting transcriptional repressor MAD3
  • class C basic helix-loop-helix protein 13
  • max dimerization protein 3
  • max dimerizer 3
  • max-associated protein 3
  • Mad3
  • max-interacting transcriptional repressor MAD3
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