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MYB Produits

(V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Catégories

This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].

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Catégories MYB en vedette

MYB Anticorps

High quality antibodies with extensive validation data.

MYB Kits ELISA

Reliable ELISA kits for a wide range of species.

MYB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MYB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
N° du produit ABIN190759
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6263449
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (1)
  • (2)
N° du produit ABIN6263448
Quantité 100 μL
Fiche technique Fiche technique

MYB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971104
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648636
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380230
Quantité 2 x 96 tests
Fiche technique Fiche technique

MYB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311699
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1311697
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413670
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MYB

Huang, Zhang, Hou, Wang, Liu, Zhang, Chen, Zhu: "LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 194, (2018) (PubMed).

Srivastava, Bhardwaj, Arora, Singh, Azim, Tyagi, Carter, Wang, Singh: "MYB is a novel regulator of pancreatic tumour growth and metastasis." dans: British journal of cancer, Vol. 113, Issue 12, pp. 1694-703, (2015) (PubMed).

Volpe, Clarke, Garcìa, Walton, Vegiopoulos, Del Pozzo, ONeill, Frampton, Dumon: "Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138257, (2015) (PubMed).

Srivastava, Bhardwaj, Singh, Arora, McClellan, Grizzle, Reed, Singh: "Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance." dans: Carcinogenesis, Vol. 33, Issue 6, pp. 1149-57, (2012) (PubMed).

Deisenroth, Thorner, Enomoto, Perou, Zhang: "Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53." dans: Molecular and cellular biology, Vol. 30, Issue 16, pp. 3981-93, (2010) (PubMed).

Fahl, Crittenden, Allman, Bender: "c-Myb is required for pro-B cell differentiation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 9, pp. 5582-92, (2009) (PubMed).

Chen, Xu, Zeng, Li, Yin, Chen, Shao, Jin: "c-myb activates CXCL12 transcription in T47D and MCF7 breast cancer cells." dans: Acta biochimica et biophysica Sinica, Vol. 42, Issue 1, pp. 1-7, (2009) (PubMed).

Clappier, Cuccuini, Kalota, Crinquette, Cayuela, Dik, Langerak, Montpellier, Nadel, Walrafen, Delattre, Aurias, Leblanc, Dombret, Gewirtz, Baruchel, Sigaux, Soulier: "The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children." dans: Blood, Vol. 110, Issue 4, pp. 1251-61, (2007) (PubMed).

Sramko, Markus, Kabát, Wolff, Bies: "Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins." dans: The Journal of biological chemistry, Vol. 281, Issue 52, pp. 40065-75, (2006) (PubMed).

Close, Game, Clark, Bergounioux, Gerovassili, Thein: "Genome annotation of a 1.5 Mb region of human chromosome 6q23 encompassing a quantitative trait locus for fetal hemoglobin expression in adults." dans: BMC genomics, Vol. 5, Issue 1, pp. 33, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à MYB

MYB proto-oncogene, transcription factor (MYB), myeloblastosis oncogene (Myb), MYB proto-oncogene, transcription factor S homeolog (myb.S), v-myb avian myeloblastosis viral oncogene homolog (myb), MYB proto-oncogene, transcription factor (Myb), AI550390, c-myb, c-myb_CDS, Cmyb, cmyb, efg, M16449, xmyb

Protein level used designations for MYB

  • c-myb protein (140 AA)
  • c-myb10A_CDS
  • c-myb13A_CDS
  • c-myb14A_CDS
  • c-myb8B_CDS
  • proto-oncogene c-Myb
  • transcriptional activator Myb
  • gag-myb protein
  • myb proto-oncogene protein
  • myeloblastosis proto-oncogene product
  • tumor-specific myb protein
  • C-myb
  • myeloblastosis oncogene
  • Avian myeloblastosis viral (v-myb) oncogene homolog
  • v-myb myeloblastosis viral oncogene homolog (avian)
  • transcriptional activator Myb-like
  • DNA-binding transcriptional regulator
  • c-myb proto-oncogene
  • transcription factor cmyb
  • v-myb myeloblastosis viral oncogene homolog
  • v-myb avian myeloblastosis viral oncogene homolog
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