MYCN Produits
(N-Myc Proto-Oncogene Protein (MYCN))
Catégories
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].
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Catégories MYCN en vedette
MYCN Anticorps
High quality antibodies with extensive validation data.
MYCN Kits ELISA
Reliable ELISA kits for a wide range of species.
MYCN Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MYCN recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
- (1)
N° du produit
ABIN760676
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
N° du produit
ABIN1680957
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (6)
N° du produit
ABIN7193585
Quantité
100 μL
Fiche technique
Fiche technique
MYCN recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6974813
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5591497
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN2870005
Quantité
96 tests
Fiche technique
Fiche technique
MYCN recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (4)
- (1)
N° du produit
ABIN1311728
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124095
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311730
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MYCN
: "P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma." dans: Molecular & cellular proteomics : MCP, Vol. 22, Issue 3, pp. 100504, (2023) (PubMed).: "SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells." dans: Scientific reports, Vol. 6, pp. 31615, (2016) (PubMed).
: "Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease." dans: Oncotarget, Vol. 7, Issue 14, pp. 18605-19, (2016) (PubMed).
: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." dans: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).
: "p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma." dans: Molecular cancer research : MCR, Vol. 13, Issue 3, pp. 584-91, (2015) (PubMed).
: "Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma." dans: Molecular oncology, (2015) (PubMed).
: "Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells." dans: The Journal of biological chemistry, Vol. 290, Issue 10, pp. 6106-19, (2015) (PubMed).
: "The role of histone demethylase KDM4B in Myc signaling in neuroblastoma." dans: Journal of the National Cancer Institute, Vol. 107, Issue 6, pp. djv080, (2015) (PubMed).
: "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3? resulting in the stabilization of MYCN in human neuroblastomas." dans: PLoS genetics, Vol. 10, Issue 1, pp. e1003996, (2014) (PubMed).
: "Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells." dans: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 7, pp. 1115-31, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à MYCN
MYCN proto-oncogene, bHLH transcription factor (MYCN), v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn), MYCN proto-oncogene, bHLH transcription factor (Mycn), olfactory receptor 8S1 (LOC515887), MYCN proto-oncogene, bHLH transcription factor (mycn), MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S), bHLHe37, c-nmyc, fb57a02, MODED, mycn, mycn-a, mycn-b, mycna, MYCNOT, N-myc, Nmuc1, NMYC, Nmyc, Nmyc-1, Nmyc1, nmyc1, ODED, wu:fb57a02, XN-myc, xN-myc1, XNmyc, zgc:85706Protein level used designations for MYCN
- N-myc proto-oncogene protein
- class E basic helix-loop-helix protein 37
- neuroblastoma MYC oncogene
- neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
- oncogene NMYC
- pp65/67
- v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
- N-myc protein
- neuroblastoma myc-related oncogene 1
- Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc)
- Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc)
- N-myc-like protein
- v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
- MYCN proto-oncogene, bHLH transcription factor S homeolog
- v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a
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