NAIP Produits
(NLR Family, Apoptosis Inhibitory Protein (NAIP))
Catégories
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length\; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories NAIP en vedette
NAIP Anticorps
High quality antibodies with extensive validation data.
NAIP Kits ELISA
Reliable ELISA kits for a wide range of species.
NAIP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NAIP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7145194
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN7268931
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (2)
N° du produit
ABIN7442096
Quantité
100 μL
Fiche technique
Fiche technique
NAIP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968952
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958208
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN771006
Quantité
96 tests
Fiche technique
Fiche technique
NAIP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311946
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7414174
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7394255
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NAIP
: "Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections." dans: Frontiers in microbiology, Vol. 10, pp. 2020, (2019) (PubMed).: "Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 815-9, (2015) (PubMed).
: "Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin." dans: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38460-72, (2012) (PubMed).
: "NAIP and Ipaf control Legionella pneumophila replication in human cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6808-15, (2008) (PubMed).
: "Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9." dans: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40622-8, (2004) (PubMed).
: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." dans: Nature, Vol. 426, Issue 6965, pp. 450-4, (2003) (PubMed).
: "The inhibitors of apoptosis: there is more to life than Bcl2." dans: Oncogene, Vol. 22, Issue 53, pp. 8568-80, (2003) (PubMed).
: "Angiotensin-converting enzyme 2 is an essential regulator of heart function." dans: Nature, Vol. 417, Issue 6891, pp. 822-8, (2002) (PubMed).
: "NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells." dans: Leukemia research, Vol. 26, Issue 9, pp. 857-62, (2002) (PubMed).
: "Vascular gp91(phox): beyond the endothelium." dans: Circulation research, Vol. 87, Issue 1, pp. 1-3, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à NAIP
NLR family apoptosis inhibitory protein (NAIP), NLR family, apoptosis inhibitory protein 1 (Naip1), AV364616, BIRC1, Birc1a, D13Lsd1, Naip, Naip-rs1, NLRB1, psiNAIPProtein level used designations for NAIP
- baculoviral IAP repeat-containing protein 1
- neuronal apoptosis inhibitory protein
- nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1
- psi neuronal apoptosis inhibitory protein
- baculoviral IAP repeat-containing 1
- baculoviral IAP repeat-containing 1a
- baculoviral IAP repeat-containing protein 1a
- neuronal apoptosis inhibitory protein 1
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