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Nanog Produits

(Nanog Homeobox (NANOG))
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

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Catégories Nanog en vedette

Nanog Anticorps

High quality antibodies with extensive validation data.

Nanog Kits ELISA

Reliable ELISA kits for a wide range of species.

Nanog Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Nanog recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC, ICC, IHC (p), IP, IHC (fro)
Validations
  • (6)
  • (14)
N° du produit ABIN2854880
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN2177828
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, FACS, ICC
Validations
  • (9)
N° du produit ABIN7155816
Quantité 100 μL
Fiche technique Fiche technique

Nanog recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968797
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958029
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validations
  • (2)
N° du produit ABIN5526712
Quantité 96 tests
Fiche technique Fiche technique

Nanog recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124111
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667504
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2565285
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Nanog

Wang, Jing, Hu, Yu, Yao, Li, Cheng: "Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma." dans: Journal of cellular and molecular medicine, (2021) (PubMed).

Tan, Xu, Du, Wu, Guo, Huang, Zhu, Li, Lin, Yao: "SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG." dans: Cell death & disease, Vol. 10, Issue 11, pp. 794, (2020) (PubMed).

Moreno-Marín, Barrasa, Morales-Hernández, Paniagua, Blanco-Fernández, Merino, Fernández-Salguero: "Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis." dans: Scientific reports, Vol. 7, Issue 1, pp. 10420, (2019) (PubMed).

Ahmed, El-Sayed, Chen, Zhao, Jin, Zuo, Zhang, Li: "Direct conversion of mouse embryonic fibroblast to osteoblast cells using hLMP-3 with Yamanaka factors." dans: The international journal of biochemistry & cell biology, Vol. 106, pp. 84-95, (2019) (PubMed).

He, Wang, Zhang, Chen, Liang, Li, Zhang, Yang, Pang, Li, Huang, Qin, Pei, Sun, Zheng: "Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming." dans: Cell discovery, Vol. 5, pp. 11, (2019) (PubMed).

Castelli, Susani, Menale, Muggeo, Caldana, Strina, Cassani, Recordati, Scanziani, Ficara, Villa, Vezzoni, Paulis: "Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells." dans: Stem cells (Dayton, Ohio), Vol. 37, Issue 7, pp. 876-887, (2019) (PubMed).

Kodama, Harinath, Mihara-Tomiyama, Tominaga, Ide, Nakahara, Maeda, Igarashi, DArmiento, Chada, Imai: "Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression." dans: Biochemical and biophysical research communications, Vol. 509, Issue 4, pp. 1008-1014, (2019) (PubMed).

Glennon, Austin, Arang, Kain, Mast, Vijayan, Aitchison, Kappe, Kaushansky: "Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection." dans: Cell reports, Vol. 26, Issue 12, pp. 3391-3399.e4, (2019) (PubMed).

Daum, Brauchle, Berrio, Jurkowski, Schenke-Layland: "Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging." dans: Scientific reports, Vol. 9, Issue 1, pp. 7014, (2019) (PubMed).

Nasr, Farghaly, Elsaba, El-Mokhtar, Radwan, Elsabahy, Abdelkareem, Fakhry, Mousa: "Resistance of primary breast cancer cells with enhanced pluripotency and stem cell activity to sex hormonal stimulation and suppression." dans: The international journal of biochemistry & cell biology, Vol. 105, pp. 84-93, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à Nanog

Nanog homeobox (Nanog), Nanog homeobox (NANOG), nanog homeobox (nanog), 2410002E02Rik, ecat4, ENK, hacp, NANOG, wu:fd19e04, wu:fd20a07, zgc:193933

Protein level used designations for Nanog

  • ES cell-associated protein 4
  • early embryo specific expression NK family
  • early embryo specific expression NK-type homeobox protein
  • homeobox protein NANOG
  • homeobox transcription factor Nanog
  • hNanog
  • homeobox transcription factor Nanog-delta 48
  • homeobox transcription factor NANOG
  • Nanog homeobox
  • nanog homeobox transcription factor
  • homeodomain transcription factor Nanog
  • LOW QUALITY PROTEIN: homeobox protein NANOG
  • fd20a07
  • nanog homeobox
  • ovary-expressed homeobox protein
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