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NBR1 Produits

(Neighbor of BRCA1 Gene 1 (NBR1))

Catégories

The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories NBR1 en vedette

NBR1 Anticorps

High quality antibodies with extensive validation data.

NBR1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NBR1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NBR1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (5)
N° du produit ABIN1680974
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
N° du produit ABIN561705
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (7)
  • (2)
N° du produit ABIN517601
Quantité 100 μg
Fiche technique Fiche technique

NBR1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968819
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1145033
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6208870
Quantité 96 tests
Fiche technique Fiche technique

NBR1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312051
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1780821
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094033
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NBR1

Di Rienzo, Antonioli, Fusco, Liu, Mari, Orhon, Refolo, Germani, Corazzari, Romagnoli, Ciccosanti, Mandriani, Pellico, De La Torre, Ding, Dentice, Neri, Ferlini, Reggiori, Kulesz-Martin, Piacentini et al.: "Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. ..." dans: Science advances, Vol. 5, Issue 5, pp. eaau8857, (2019) (PubMed).

Kim, Hwang, Cho, Chi, Park, Chang, Whang: "Depletion of NBR1 in urothelial carcinoma cells enhances rapamycin-induced apoptosis through impaired autophagy and mitochondrial dysfunction." dans: Journal of cellular biochemistry, (2019) (PubMed).

Romagnoli, Petruccioli, Palucci, Camassa, Carata, Petrone, Mariano, Sali, Dini, Girardi, Delogu, Goletti, Fimia: "Clinical isolates of the modern Mycobacterium tuberculosis lineage 4 evade host defense in human macrophages through eluding IL-1β-induced autophagy." dans: Cell death & disease, Vol. 9, Issue 6, pp. 624, (2018) (PubMed).

Kenific, Stehbens, Goldsmith, Leidal, Faure, Ye, Wittmann, Debnath: "NBR1 enables autophagy-dependent focal adhesion turnover." dans: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).

Jiang, Hara-Kuge, Yamashita, Fujiki: "Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).

Murrow, Malhotra, Debnath: "ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function." dans: Nature cell biology, Vol. 17, Issue 3, pp. 300-10, (2015) (PubMed).

Malhotra, Warne, Salas, Xu, Debnath: "Loss of Atg12, but not Atg5, in pro-opiomelanocortin neurons exacerbates diet-induced obesity." dans: Autophagy, Vol. 11, Issue 1, pp. 145-54, (2015) (PubMed).

Dowdle, Nyfeler, Nagel, Elling, Liu, Triantafellow, Menon, Wang, Honda, Pardee, Cantwell, Luu, Cornella-Taracido, Harrington, Fekkes, Lei, Fang, Digan, Burdick, Powers, Helliwell, DAquin, Bastien et al.: "Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. ..." dans: Nature cell biology, Vol. 16, Issue 11, pp. 1069-79, (2014) (PubMed).

Rué, López-Soop, Gelpi, Martínez-Vicente, Alberch, Pérez-Navarro: "Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease." dans: Neurobiology of disease, Vol. 52, pp. 219-28, (2013) (PubMed).

Deosaran, Larsen, Hua, Sargent, Wang, Kim, Lamark, Jauregui, Law, Lippincott-Schwartz, Brech, Johansen, Kim: "NBR1 acts as an autophagy receptor for peroxisomes." dans: Journal of cell science, Vol. 126, Issue Pt 4, pp. 939-52, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à NBR1

neighbor of brca1 gene 1a (nbr1a), neighbor of BRCA1 gene 1 L homeolog (nbr1.L), NBR1, autophagy cargo receptor (NBR1), neighbor of Brca1 gene 1 (Nbr1), NBR1, autophagy cargo receptor (Nbr1), 1A1-3B, Ca125, fa99f08, M17S2, MGC69008, mKIAA0049, NBR1, RGD1311421, wu:fa99f08

Protein level used designations for NBR1

  • neighbor of BRCA1 gene 1
  • next to BRCA1 gene 1 protein
  • next to BRCA1 gene 1 protein-like
  • cell migration-inducing gene 19 protein
  • membrane component chromosome 17 surface marker 2
  • membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
  • migration-inducing protein 19
  • neighbor of BRCA1 gene 1 protein
  • protein 1A1-3B
  • membrane component chromosome 17 surface marker 2 homolog
  • next to the Brca1
  • ovarian carcinoma antigen CA125
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