NCF2 Produits
(Neutrophil Cytosolic Factor 2 (NCF2))
Catégories
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010].
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Catégories NCF2 en vedette
NCF2 Anticorps
High quality antibodies with extensive validation data.
NCF2 Kits ELISA
Reliable ELISA kits for a wide range of species.
NCF2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NCF2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (4)
N° du produit
ABIN7161498
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN6263535
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN3021641
Quantité
100 μL
Fiche technique
Fiche technique
NCF2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958175
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951326
Quantité
96 tests
Fiche technique
Fiche technique
NCF2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312095
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312097
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7415524
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NCF2
: "Testosterone improves erectile function through inhibition of reactive oxygen species generation in castrated rats." dans: PeerJ, Vol. 4, pp. e2000, (2016) (PubMed).: "Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value." dans: British journal of cancer, Vol. 104, Issue 1, pp. 110-9, (2011) (PubMed).
: "Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating" dans: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33644-53, (1999) (PubMed).
: "Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways." dans: The Journal of biological chemistry, Vol. 272, Issue 27, pp. 17204-8, (1997) (PubMed).
: "NADPH oxidase activity is independent of p47phox in vitro." dans: The Journal of biological chemistry, Vol. 271, Issue 37, pp. 22578-82, (1996) (PubMed).
: "Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10650-4, (1994) (PubMed).
: "Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src." dans: Science (New York, N.Y.), Vol. 248, Issue 4956, pp. 727-30, (1990) (PubMed).
Synonymes et noms alternatifs relatifs à NCF2
neutrophil cytosolic factor 2 (NCF2), neutrophil cytosolic factor 2 L homeolog (ncf2.L), neutrophil cytosolic factor 2 (ncf2), neutrophil cytosolic factor 2 (p67phox), neutrophil cytosol factor 2 (VDBG_06643), hypothetical protein (PGTG_05816), neutrophil cytosolic factor 2 (LOC100136240), neutrophil cytosolic factor 2 (Ncf2), MGC81877, NCF-2, Ncf-2, noxa2, NOXA2, p67-phox, P67-PHOX, p67phox, P67PHOX, zgc:158405Protein level used designations for NCF2
- neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
- neutrophil cytosolic factor 2
- neutrophil cytosol factor 2
- predicted neutrophil cytosolic factor 2
- p67phox
- p67-phox
- NADPH oxidase cytosolic protein p67phox
- NADPH oxidase cytosolic protein
- 67 kDa neutrophil oxidase factor
- NADPH oxidase activator 2
- chronic granulomatous disease, autosomal 2
- neutrophil NADPH oxidase factor 2
- neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
- NADPH oxidase subunit (67 kD)
- NADPH oxidase subunit (67kDa)
- NCF-2
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