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NCOA1 Produits

(Nuclear Receptor Coactivator 1 (NCOA1))
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories NCOA1 en vedette

NCOA1 Anticorps

High quality antibodies with extensive validation data.

NCOA1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NCOA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NCOA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN3021492
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN391825
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (2)
N° du produit ABIN7269005
Quantité 100 μL
Fiche technique Fiche technique

NCOA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969007
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969006
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method
Validations
N° du produit ABIN1145493
Quantité 96 tests
Fiche technique Fiche technique

NCOA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312124
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422733
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
N° du produit ABIN2732662
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NCOA1

Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: "Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment." dans: Cell reports, Vol. 18, Issue 8, pp. 1946-1957, (2017) (PubMed).

Lau, Yang, Chang: "Isoform-selective activation of human constitutive androstane receptor by Ginkgo biloba extract: functional analysis of the SV23, SV24, and SV25 splice variants." dans: The Journal of pharmacology and experimental therapeutics, Vol. 339, Issue 2, pp. 704-15, (2011) (PubMed).

Lau, Yang, Rajaraman, Baucom, Chang: "Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor." dans: The Journal of pharmacology and experimental therapeutics, Vol. 336, Issue 3, pp. 816-26, (2011) (PubMed).

Lau, Yang, Rajaraman, Baucom, Chang: "Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides." dans: The Journal of pharmacology and experimental therapeutics, Vol. 335, Issue 3, pp. 771-80, (2010) (PubMed).

Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: "Androgen modulation of coregulator expression in prostate cancer cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).

Privalsky, Lee, Hahm, Young, Fong, Chan: "The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors." dans: The Journal of biological chemistry, Vol. 284, Issue 29, pp. 19554-63, (2009) (PubMed).

Amita, Takahashi, Tsutsumi, Ohta, Takata, Henmi, Hara, Igarashi, Takahashi, Kurachi: "Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate." dans: Endocrinology, Vol. 151, Issue 1, pp. 394-405, (2009) (PubMed).

Lavery, McEwan: "Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a." dans: Biochemistry, Vol. 47, Issue 11, pp. 3352-9, (2008) (PubMed).

Wang, Zhang, Nordeen, Shapiro: "In vitro fluorescence anisotropy analysis of the interaction of full-length SRC1a with estrogen receptors alpha and beta supports an active displacement model for coregulator utilization." dans: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2765-75, (2007) (PubMed).

Jaber, Gao, Huang, Karmakar, Smith et al.: "The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding ..." dans: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2695-710, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à NCOA1

nuclear receptor coactivator 1 (NCOA1), nuclear receptor coactivator 1 (ncoa1), nuclear receptor coactivator 1 (Ncoa1), bHLHe42, bHLHe74, F-SRC-1, KAT13A, NCOA1, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRC-1, SRC1

Protein level used designations for NCOA1

  • Hin-2 protein
  • PAX3/NCOA1 fusion protein
  • class E basic helix-loop-helix protein 74
  • renal carcinoma antigen NY-REN-52
  • steroid receptor coactivator-1
  • nuclear receptor coactivator 1
  • steroid receptor coactivator 1
  • DKEY-34F16.7
  • SRC1
  • NCoA-1
  • SRC-a/NCoA-1
  • mNRC-1
  • nuclear receptor coactivator protein 1
  • SRC-1
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