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NDC80 Produits

(NDC80 Kinetochore Complex Component Homolog (NDC80))

Catégories

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011].

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Catégories NDC80 en vedette

NDC80 Anticorps

High quality antibodies with extensive validation data.

NDC80 Kits ELISA

Reliable ELISA kits for a wide range of species.

NDC80 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NDC80 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
N° du produit ABIN564521
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6263548
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN184821
Quantité 100 μg
Fiche technique Fiche technique

NDC80 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648262
Quantité 96 tests
Fiche technique Fiche technique

NDC80 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312158
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312160
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3137068
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NDC80

Raab, Sanhaji, Matthess, Hörlin, Lorenz, Dötsch, Habbe, Waidmann, Kurunci-Csacsko, Firestein, Becker, Strebhardt: "PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells." dans: Nature communications, Vol. 9, Issue 1, pp. 1106, (2018) (PubMed).

DeLuca, Meppelink, Broad, Mick, Peersen, Pektas, Lens, DeLuca: "Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics." dans: The Journal of cell biology, Vol. 217, Issue 1, pp. 163-177, (2018) (PubMed).

Dumitru, Rusin, Clark, Kettenbach, Compton: "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability." dans: eLife, Vol. 6, (2017) (PubMed).

Tauchman, Boehm, DeLuca: "Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells." dans: Nature communications, Vol. 6, pp. 10036, (2015) (PubMed).

Yao, Kondoh, Natsume, Yamanaka, Inoue, Toki, Takagi, Shimizu, Yamori, Osada, Noda: "A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells." dans: Oncogene, Vol. 33, Issue 33, pp. 4242-52, (2014) (PubMed).

Sivakumar, Daum, Tipton, Rankin, Gorbsky: "The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit." dans: Molecular biology of the cell, Vol. 25, Issue 5, pp. 594-605, (2014) (PubMed).

Kleyman, Kabeche, Compton: "STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments." dans: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4225-33, (2014) (PubMed).

Hwang, Peddibhotla, McHenry, Chang, Yochum, Park, Sears, Vargo-Gogola: "P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells." dans: Cancers, Vol. 4, Issue 2, pp. 475-89, (2013) (PubMed).

Maier, Kirsch, Anderhub, Zentgraf, Krämer: "The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells." dans: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 9, pp. 1457-71, (2013) (PubMed).

Kabeche, Compton: "Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation." dans: Nature, Vol. 502, Issue 7469, pp. 110-3, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à NDC80

NDC80, kinetochore complex component (NDC80), CG9938 gene product from transcript CG9938-RA (Ndc80), spindle pole body protein Ndc80 (ndc80), kinetochore protein Ndc80 (ndc80), NDC80 homolog, kinetochore complex component (S. cerevisiae) (ndc80), NDC80 kinetochore complex component (Ndc80), NDC80 kinetochore complex component (ndc80), NDC80 kinetochore complex component S homeolog (ndc80.S), 2610020P18Rik, AV139730, CG9938, Dmel\\CG9938, dmNdc80, dNdc80, HEC, Hec1, hec1, HEC1, HsHec1, hsNDC80, KNTC2, Kntc2, kntc2, kntc2l, ndc10, NDC80, tid3, TID3, wu:fb52e02, zgc:111801

Protein level used designations for NDC80

  • kinetochore associated 2
  • CG9938-PA
  • Hec1
  • Ndc80-PA
  • NDC80 homolog, kinetochore complex component (S. cerevisiae)
  • NDC80 homolog, kinetochore complex component
  • kinetochore protein NDC80 homolog
  • kinetochore protein Ndc80
  • Kinetochore protein NDC80 homolog
  • highly expressed in cancer, rich in leucine heptad repeats
  • kinetochore protein Hec1
  • kinetochore-associated protein 2
  • HEC (highly expressed in cancer)
  • NDC80 kinetochore complex component homolog
  • highly expressed in cancer protein
  • retinoblastoma-associated protein HEC
  • kinetochore spindle checkpoint protein Ndc80
  • xNdc80
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