NDC80 Produits
(NDC80 Kinetochore Complex Component Homolog (NDC80))
Catégories
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011].
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Catégories NDC80 en vedette
NDC80 Anticorps
High quality antibodies with extensive validation data.
NDC80 Kits ELISA
Reliable ELISA kits for a wide range of species.
NDC80 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NDC80 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN564521
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
N° du produit
ABIN6263548
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN184821
Quantité
100 μg
Fiche technique
Fiche technique
NDC80 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648262
Quantité
96 tests
Fiche technique
Fiche technique
NDC80 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312158
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312160
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3137068
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NDC80
: "PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells." dans: Nature communications, Vol. 9, Issue 1, pp. 1106, (2018) (PubMed).: "Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics." dans: The Journal of cell biology, Vol. 217, Issue 1, pp. 163-177, (2018) (PubMed).
: "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability." dans: eLife, Vol. 6, (2017) (PubMed).
: "Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells." dans: Nature communications, Vol. 6, pp. 10036, (2015) (PubMed).
: "A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells." dans: Oncogene, Vol. 33, Issue 33, pp. 4242-52, (2014) (PubMed).
: "The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit." dans: Molecular biology of the cell, Vol. 25, Issue 5, pp. 594-605, (2014) (PubMed).
: "STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments." dans: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4225-33, (2014) (PubMed).
: "P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells." dans: Cancers, Vol. 4, Issue 2, pp. 475-89, (2013) (PubMed).
: "The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells." dans: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 9, pp. 1457-71, (2013) (PubMed).
: "Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation." dans: Nature, Vol. 502, Issue 7469, pp. 110-3, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à NDC80
NDC80, kinetochore complex component (NDC80), CG9938 gene product from transcript CG9938-RA (Ndc80), spindle pole body protein Ndc80 (ndc80), kinetochore protein Ndc80 (ndc80), NDC80 homolog, kinetochore complex component (S. cerevisiae) (ndc80), NDC80 kinetochore complex component (Ndc80), NDC80 kinetochore complex component (ndc80), NDC80 kinetochore complex component S homeolog (ndc80.S), 2610020P18Rik, AV139730, CG9938, Dmel\\CG9938, dmNdc80, dNdc80, HEC, Hec1, hec1, HEC1, HsHec1, hsNDC80, KNTC2, Kntc2, kntc2, kntc2l, ndc10, NDC80, tid3, TID3, wu:fb52e02, zgc:111801Protein level used designations for NDC80
- kinetochore associated 2
- CG9938-PA
- Hec1
- Ndc80-PA
- NDC80 homolog, kinetochore complex component (S. cerevisiae)
- NDC80 homolog, kinetochore complex component
- kinetochore protein NDC80 homolog
- kinetochore protein Ndc80
- Kinetochore protein NDC80 homolog
- highly expressed in cancer, rich in leucine heptad repeats
- kinetochore protein Hec1
- kinetochore-associated protein 2
- HEC (highly expressed in cancer)
- NDC80 kinetochore complex component homolog
- highly expressed in cancer protein
- retinoblastoma-associated protein HEC
- kinetochore spindle checkpoint protein Ndc80
- xNdc80
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