NEDD9 Produits
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
Catégories
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Catégories NEDD9 en vedette
NEDD9 Anticorps
High quality antibodies with extensive validation data.
NEDD9 Kits ELISA
Reliable ELISA kits for a wide range of species.
NEDD9 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NEDD9 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (9)
N° du produit
ABIN3023331
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (3)
N° du produit
ABIN129518
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
N° du produit
ABIN561951
Quantité
50 μg
Fiche technique
Fiche technique
NEDD9 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968848
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1131949
Quantité
96 tests
Fiche technique
Fiche technique
NEDD9 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312332
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312334
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3090359
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NEDD9
: "Overexpression of NEDD9 promotes cell invasion and metastasis in hepatocellular carcinoma." dans: Clinics and research in hepatology and gastroenterology, Vol. 41, Issue 6, pp. 677-686, (2018) (PubMed).: "Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability." dans: Immunology and cell biology, Vol. 94, Issue 10, pp. 981-993, (2016) (PubMed).
: "NEDD9 overexpression correlates with poor prognosis in gastric cancer." dans: Tumour biology, Vol. 35, Issue 7, pp. 6351-6, (2014) (PubMed).
: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." dans: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).
: "The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC." dans: PLoS ONE, Vol. 8, Issue 9, pp. e74594, (2013) (PubMed).
: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).
: "Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation." dans: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21526-36, (2010) (PubMed).
: "Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. ..." dans: Human molecular genetics, Vol. 17, Issue 5, pp. 759-67, (2008) (PubMed).
: "Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene." dans: Cell, Vol. 125, Issue 7, pp. 1269-81, (2006) (PubMed).
: "The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking." dans: Immunity, Vol. 25, Issue 6, pp. 907-18, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à NEDD9
neural precursor cell expressed, developmentally down-regulated 9 (NEDD9), neural precursor cell expressed, developmentally down-regulated 9 (Nedd9), neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), CAS-L, Cas-L, CAS2, CASL, CasL, CASS2, E230025G09Rik, HEF1, NEDD9Protein level used designations for NEDD9
- neural precursor cell expressed, developmentally down-regulated 9
- enhancer of filamentation 1 homolog
- Cas scaffolding protein family member 2
- Crk-associated substrate related protein Cas-L
- Enhancer of filamentation 1 p55
- cas-like docking
- enhancer of filamentation 1
- neural precursor cell expressed developmentally down-regulated protein 9
- p130Cas-related protein
- renal carcinoma antigen NY-REN-12
- neural precursor cell expressed, developmentally down-regulated gene 9
- CRK-associated substrate-related protein
- Crk-associated substrate lymphocyte-specific protein
- NEDD-9
- mEF1
- p105
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