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NEFL Produits

(Neurofilament, Light Polypeptide (NEFL))

Catégories

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008].

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Catégories NEFL en vedette

NEFL Anticorps

High quality antibodies with extensive validation data.

NEFL Kits ELISA

Reliable ELISA kits for a wide range of species.

NEFL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NEFL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (2)
  • (7)
N° du produit ABIN969548
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (8)
N° du produit ABIN3020809
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
N° du produit ABIN7268867
Quantité 100 μL
Fiche technique Fiche technique

NEFL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958109
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6976127
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6958108
Quantité 96 tests
Fiche technique Fiche technique

NEFL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7092803
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7092809
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124149
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NEFL

Hołub, Kędzierska, Muras-Szwedziak, Nowicki: "Serum neurofilament light chain is not a useful biomarker of central nervous system involvement in women with Fabry disease." dans: Intractable & rare diseases research, Vol. 10, Issue 4, pp. 276-282, (2021) (PubMed).

Kimura, Takemura, Yamamoto, Hayashi, Saito, Shimohata: "Cytokines and biological markers in autoimmune GFAP astrocytopathy: The potential role for pathogenesis and therapeutic implications." dans: Journal of neuroimmunology, Vol. 334, pp. 576999, (2020) (PubMed).

Lin, Kuo, Chen, Huang: "RBFOX3/NeuN is dispensable for visual function." dans: PLoS ONE, Vol. 13, Issue 2, pp. e0192355, (2018) (PubMed).

Candy, Ma, McMahon, Farrell, Mychasiuk: "Staying in the game: a pilot study examining the efficacy of protective headgear in an animal model of mild traumatic brain injury (mTBI)." dans: Brain injury, Vol. 31, Issue 11, pp. 1521-1529, (2018) (PubMed).

Puentes, van der Star, Boomkamp, Kipp, Boon, Bosca, Raffel, Gnanapavan, van der Valk, Stephenson, Barnett, Baker, Amor: "Neurofilament light as an immune target for pathogenic antibodies." dans: Immunology, Vol. 152, Issue 4, pp. 580-588, (2017) (PubMed).

Raphael, Webb, Gomez-Rivera, Chase Huizar, Gupta, Arulanandam, Wang, Haskins, Forsthuber: "Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis." dans: Frontiers in immunology, Vol. 8, pp. 812, (2017) (PubMed).

Iłżecki, Iłżecka, Przywara, Terlecki, Grabarska, Stepulak, Zubilewicz: "Effect of carotid endarterectomy on brain damage markers." dans: Acta neurologica Scandinavica, (2016) (PubMed).

Altabella, Sbriccoli, Zoratto, Poleggi, Vinci, Lacivita, Leopoldo, Laviola, Cardone, Canese, Adriani: "Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study." dans: Frontiers in behavioral neuroscience, Vol. 8, pp. 427, (2015) (PubMed).

Aboelenain, Kawahara, Balboula, Montasser, Zaabel, Okuda, Takahashi: "Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle." dans: The Journal of reproduction and development, Vol. 61, Issue 3, pp. 229-36, (2015) (PubMed).

Wang, Hsieh, Huang, Chin, Chou, Tung, Chen, Lee, Gau, Huang: "RBFOX3/NeuN is Required for Hippocampal Circuit Balance and Function." dans: Scientific reports, Vol. 5, pp. 17383, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à NEFL

neurofilament light (NEFL), neurofilament, light polypeptide (NEFL), neurofilament, light polypeptide b (neflb), neurofilament, light polypeptide (Nefl), neurofilament light (Nefl), neurofilament, light L homeolog (nefl.L), AI847934, CMT1F, CMT2E, NEFL, nefl, NF-L, NF68, Nfl, NFL, XNF-L, zgc:136626

Protein level used designations for NEFL

  • neurofilament, light polypeptide 68kDa
  • neurofilament, light polypeptide
  • neurofilament light polypeptide
  • 68 kDa neurofilament protein
  • neurofilament protein L
  • neurofilament triplet L protein
  • light molecular weight neurofilament protein
  • neurofilament protein, light chain
  • neurofilament subunit NF-L
  • NF-L
  • micro glutamic acid-rich protein
  • neurofilament protein
  • Neurofilament triplet L protein
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