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NEK2 Produits

(NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))

Catégories

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011].

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Catégories NEK2 en vedette

NEK2 Anticorps

High quality antibodies with extensive validation data.

NEK2 Kits ELISA

Reliable ELISA kits for a wide range of species.

NEK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NEK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7439456
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (5)
N° du produit ABIN561955
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN561956
Quantité 100 μg
Fiche technique Fiche technique

NEK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5525181
Quantité 96 tests
Fiche technique Fiche technique

NEK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312356
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509038
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7416697
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NEK2

Zhao, Han, Liu, Cui, Chen: "MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2." dans: Thoracic cancer, Vol. 8, Issue 4, pp. 304-311, (2018) (PubMed).

Lin, Zhou, Jiang, Liu, Wang, Zheng, Zhou, Li, Cai: "NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma." dans: Oncology reports, Vol. 36, Issue 2, pp. 853-62, (2017) (PubMed).

Zeng, Han, Wang, Cai, Huang, Luo, Liu, Zhuo, Dai, Zhao, Liang, Zhong: "Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer." dans: BMC urology, Vol. 15, pp. 90, (2015) (PubMed).

Zhong, Guan, Dong, Yang, Liu, Zhang: "Examining Nek2 as a better proliferation marker in non-small cell lung cancer prognosis." dans: Tumour biology, Vol. 35, Issue 7, pp. 7155-62, (2014) (PubMed).

Zhong, Guan, Liu, Zhang: "Aberrant expression of NEK2 and its clinical significance in non-small cell lung cancer." dans: Oncology letters, Vol. 8, Issue 4, pp. 1470-1476, (2014) (PubMed).

Naro, Barbagallo, Chieffi, Bourgeois, Paronetto, Sette: "The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival." dans: Nucleic acids research, Vol. 42, Issue 5, pp. 3218-27, (2014) (PubMed).

Jeong, Lee, Park, Han, Jang, Lim, Lee, Yang: "Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity." dans: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 28-40, (2014) (PubMed).

van Ree, Jeganathan, Malureanu, van Deursen: "Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation." dans: The Journal of cell biology, Vol. 188, Issue 1, pp. 83-100, (2010) (PubMed).

Barbagallo, Paronetto, Franco, Chieffi, Dolci, Fry, Geremia, Sette: "Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas." dans: The Journal of pathology, Vol. 217, Issue 3, pp. 431-41, (2009) (PubMed).

Wu, Baxter, Wattam, Hayward, Fardilha, Knebel, Ford, da Cruz e Silva, Fry: "Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase." dans: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26431-40, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à NEK2

NIMA related kinase 2 (NEK2), NIMA (never in mitosis gene a)-related expressed kinase 2 (Nek2), NIMA-related kinase 2 (Nek2), NIMA-related kinase 2 (NEK2), AA617254, ATNEK2, C77054, HsPK21, NEK2A, NIMA-RELATED KINASE2, NIMA-related kinase 2, NLK1, T9J14.24, T9J14_24

Protein level used designations for NEK2

  • NIMA (never in mitosis gene a)-related kinase 2
  • NIMA - related expressed kinase 2
  • NIMA-related expressed kinase 2
  • NIMA-related kinase 2
  • Nek2 kinase
  • never in mitosis A-related kinase 2
  • nimA-related protein kinase 2
  • serine/threonine-protein kinase Nek2
  • serine/threonine protein kinase Nek2
  • nimA-like protein kinase 1
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