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NEU1 Produits

(Sialidase 1 (Lysosomal Sialidase) (NEU1))
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008].

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Catégories NEU1 en vedette

NEU1 Anticorps

High quality antibodies with extensive validation data.

NEU1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NEU1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NEU1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
N° du produit ABIN7438058
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (9)
N° du produit ABIN1491548
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (5)
N° du produit ABIN1774878
Quantité 100 μg
Fiche technique Fiche technique

NEU1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6973751
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5518637
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN511750
Quantité 96 tests
Fiche technique Fiche technique

NEU1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125087
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312399
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7394420
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NEU1

Demir, Özcan, Balat, Öztürk, Uğur, Gündüz, Taysi: "Assessment of total sialic acid levels in patients with hyperemesis gravidarum: a preliminary study." dans: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 38, Issue 4, pp. 532-535, (2018) (PubMed).

Luzina, Lockatell, Hyun, Kopach, Kang, Noor, Liu, Lillehoj, Lee, Miranda-Ribera, Todd, Goldblum, Atamas: "Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 310, Issue 10, pp. L940-54, (2017) (PubMed).

Hyun, Liu, Liu, Cross, Verceles, Magesh, Kommagalla, Kona, Ando, Luzina, Atamas, Piepenbrink, Sundberg, Guang, Ishida, Lillehoj, Goldblum: "The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo." dans: Glycobiology, Vol. 26, Issue 8, pp. 834-49, (2016) (PubMed).

Li, Ma, Sarker, McClane: "CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718." dans: mBio, Vol. 4, Issue 5, pp. e00770-13, (2013) (PubMed).

Caciotti, Di Rocco, Filocamo, Grossi, Traverso, dAzzo, Cavicchi, Messeri, Guerrini, Zammarchi, Donati, Morrone: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." dans: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).

Lai, Chen, Wu Chou, Chang, Kao, Huang, Weng, Chen, Hwu, Lu: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." dans: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).

Bonten, Campos, Zaitsev, Nourse, Waddell, Lewis, Taylor, dAzzo: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à NEU1

neuraminidase 1 (NEU1), neuraminidase 1 (lysosomal sialidase) L homeolog (neu1.L), neuraminidase 1 (neu1), neuraminidase 1 (Neu1), AA407268, AA407316, Aglp, Apl, Bat-7, Bat7, G9, Map-2, MGC81958, NANH, NEU, Neu, Neu-1, SIAL1

Protein level used designations for NEU1

  • G9 sialidase
  • N-acetyl-alpha-neuraminidase 1
  • acetylneuraminyl hydrolase
  • exo-alpha-sialidase
  • lysosomal sialidase
  • sialidase-1
  • sialidase 1 (lysosomal sialidase)
  • neuraminidase
  • isotocin
  • Isotocin-neurophysin IT 1
  • neuraminidase 1
  • sialidase-1-like
  • HLA-B-associated transcript 7
  • sialidase 1
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