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Neuregulin 1 Produits

(Neuregulin 1 (NRG1))

Catégories

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009].

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Catégories Neuregulin 1 en vedette

Neuregulin 1 Anticorps

High quality antibodies with extensive validation data.

Neuregulin 1 Kits ELISA

Reliable ELISA kits for a wide range of species.

Neuregulin 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Neuregulin 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ICC, IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN3044035
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ICC, IHC (p), IHC (fro)
Validations
  • (8)
N° du produit ABIN3031973
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (4)
N° du produit ABIN6254897
Quantité 100 μL
Fiche technique Fiche technique

Neuregulin 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6958084
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6958085
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6958086
Quantité 96 tests
Fiche technique Fiche technique

Neuregulin 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN6964402
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124139
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313023
Quantité 25 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Neuregulin 1

Kang, Cheng, Zhou, Wang, Zhong, Li, Wang, Dang, Wang: "Neuregulin‑1 protects cardiac function in septic rats through multiple targets based on endothelial cells." dans: International journal of molecular medicine, Vol. 44, Issue 4, pp. 1255-1266, (2020) (PubMed).

Xie, Song, Liang, Zhang, Shi, Liu, Shi: "Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin 1." dans: Aging, Vol. 12, Issue 17, pp. 17436-17458, (2020) (PubMed).

Elfving, Müller, Oliveras, Østerbøg, Rio-Alamos, Sanchez-Gonzalez, Tobeña, Fernandez-Teruel, Aznar: "Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior." dans: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 95, pp. 109669, (2019) (PubMed).

Wang, Zhou, Wang, Yang, Fu, Zhang, Han, Li, Hu, Ge: "Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1905-1914, (2017) (PubMed).

Kawata, Morikawa, Shiosaka, Tamura: "Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation." dans: Translational psychiatry, Vol. 7, Issue 3, pp. e1052, (2017) (PubMed).

Dang, Guo, Cai, Yang, Liang, Lv, Jiang: "Effects of prolonged antipsychotic administration on neuregulin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect." dans: The Journal of toxicological sciences, Vol. 41, Issue 2, pp. 303-9, (2016) (PubMed).

Yonesaka, Hirotani, Kawakami, Takeda, Kaneda, Sakai, Okamoto, Nishio, Jänne, Nakagawa: "Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib." dans: Oncogene, Vol. 35, Issue 7, pp. 878-86, (2016) (PubMed).

Dang, Cai, Zhang, Liang, Lv, Guo, Yang, Zhu, Jiang: "Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress." dans: Physiology & behavior, Vol. 154, pp. 145-50, (2015) (PubMed).

Wang, Zhou, Ding, Zhu, Jiang, Fu, Wang, Hu, Ge: "Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6596-606, (2015) (PubMed).

Ni, Zhang, Liu, Yang, Wang, Fu, A, Zhou: "miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells." dans: Neural regeneration research, Vol. 9, Issue 8, pp. 828-36, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à Neuregulin 1

neuregulin 1 (Nrg1), neuregulin 1 (NRG1), histidine rich glycoprotein (HRG), neuregulin 1 L homeolog (nrg1.L), neuregulin 1 (nrg1), 6030402G23Rik, ARIA, D230005F13Rik, DKFZp459A1838, GGF, GGF2, GGFII, heregulin, Hgl, HGL, HRG, HRG1, HRGA, HRGalpha, MST131, NDF, NRG-1, NRG1, nrg1-A, pro-neuregulin-1, SMDF, wu:fm70e01

Protein level used designations for Neuregulin 1

  • heregulin
  • pro-neuregulin-1, membrane-bound isoform
  • type I neuregulin 1
  • type III neuregulin 1
  • neuregulin 1
  • HRG-alpha
  • heregulin-alpha
  • MSTP131
  • glial growth factor
  • heregulin, alpha (45kD, ERBB2 p185-activator)
  • neu differentiation factor
  • neuregulin 1 type IV beta 1a
  • neuregulin 1 type IV beta 3
  • pro-NRG1
  • sensory and motor neuron derived factor
  • neuregulin 1 type III beta 3
  • membrane-bound isoform
  • neuregulin 1 alpha isoform
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