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Neuregulin 3 Produits

(Neuregulin 3 (NRG3))
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009].

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Catégories Neuregulin 3 en vedette

Neuregulin 3 Anticorps

High quality antibodies with extensive validation data.

Neuregulin 3 Kits ELISA

Reliable ELISA kits for a wide range of species.

Neuregulin 3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Neuregulin 3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN3181485
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN7187474
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7191717
Quantité 100 μL
Fiche technique Fiche technique

Neuregulin 3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968854
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1571584
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951189
Quantité 96 tests
Fiche technique Fiche technique

Neuregulin 3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7396010
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3114012
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3131461
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Neuregulin 3

Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." dans: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).

Boer, Berk, Dean: "Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder." dans: Neuroscience letters, Vol. 466, Issue 1, pp. 27-9, (2009) (PubMed).

Wansbury, Panchal, James, Parry, Ashworth, Howard: "Dynamic expression of Erbb pathway members during early mammary gland morphogenesis." dans: The Journal of investigative dermatology, Vol. 128, Issue 4, pp. 1009-21, (2008) (PubMed).

Howard, Panchal, McCarthy, Ashworth: "Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification." dans: Genes & development, Vol. 19, Issue 17, pp. 2078-90, (2005) (PubMed).

Gizatullin, Muravenko, Al-Amin, Wang, Protopopov, Kashuba, Zelenin, Zabarovsky: "Human NRG3 gene Map position 10q22-q23." dans: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 8, Issue 6, pp. 560, (2001) (PubMed).

Hijazi, Young, Dougherty, Bressette, Cao, Pierce, Wong, Alimandi, King: "NRG-3 in human breast cancers: activation of multiple erbB family proteins." dans: International journal of oncology, Vol. 13, Issue 5, pp. 1061-7, (1998) (PubMed).

Zhang, Sliwkowski, Mark, Frantz, Akita, Sun, Hillan, Crowley, Brush, Godowski: "Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 18, pp. 9562-7, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à Neuregulin 3

neuregulin 3 (NRG3), neuregulin 3 (nrg3), pro-neuregulin-3, membrane-bound isoform (LOC100478170), neuregulin 3 (Nrg3), HRG3, NRG3, pro-NRG3, RGD1559678, ska

Protein level used designations for Neuregulin 3

  • neuregulin 3
  • pro-neuregulin-3, membrane-bound isoform-like
  • neuregulin 3 variant 1
  • neuregulin 3 variant 10
  • neuregulin 3 variant 11
  • neuregulin 3 variant 12
  • neuregulin 3 variant 13
  • neuregulin 3 variant 14
  • neuregulin 3 variant 3
  • neuregulin 3 variant 4
  • neuregulin 3 variant 5
  • neuregulin 3 variant 6
  • neuregulin 3 variant 7
  • neuregulin 3 variant 8
  • neuregulin 3 variant 9
  • neuregulin-3-like polypeptide
  • pro-neuregulin-3, membrane-bound isoform
  • pro-NRG3
  • scaramanga
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