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Neurofibromin 1 Produits

(Neurofibromin 1 (NF1))
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories Neurofibromin 1 en vedette

Neurofibromin 1 Anticorps

High quality antibodies with extensive validation data.

Neurofibromin 1 Kits ELISA

Reliable ELISA kits for a wide range of species.

Neurofibromin 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Neurofibromin 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IF, IHC (p), EIA
Validations
  • (4)
N° du produit ABIN953662
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
N° du produit ABIN7161270
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (2)
N° du produit ABIN561967
Quantité 100 μg
Fiche technique Fiche technique

Neurofibromin 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968859
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1144677
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1144674
Quantité 96 tests
Fiche technique Fiche technique

Neurofibromin 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1312428
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124148
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Chicken
Source Yeast
Validations
N° du produit ABIN1459018
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Neurofibromin 1

Miwa, Inoue, Sakamoto: "MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 24, Issue 5, pp. 377-389, (2019) (PubMed).

Yoshioka, Gros, Li, Kumar, Deacon, Maron, Muotri, Chi, Fu, Yu, Dowdy: "Efficient generation of human iPSCs by a synthetic self-replicative RNA." dans: Cell stem cell, Vol. 13, Issue 2, pp. 246-54, (2013) (PubMed).

Wallace, Pfefferle, Shen, McNairn, Cerami, Fallon, Rinaldi, Southard, Perou, Schimenti: "Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver." dans: Genetics, Vol. 192, Issue 2, pp. 385-96, (2012) (PubMed).

Tucker, Riccardi, Brown, Fee, Sutcliffe, Vielkind, Wechsler, Wolkenstein, Friedman: "S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas." dans: Journal of neuroscience research, Vol. 89, Issue 9, pp. 1451-60, (2011) (PubMed).

Kweh, Zheng, Kurenova, Wallace, Golubovskaya, Cance: "Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinase." dans: Molecular carcinogenesis, Vol. 48, Issue 11, pp. 1005-17, (2009) (PubMed).

Sales, Engelmayr, Johnson, Gao, Wang, Sacks, Mayer et al.: "Protein precoating of elastomeric tissue-engineering scaffolds increased cellularity, enhanced extracellular matrix protein production, and differentially regulated the phenotypes of circulating ..." dans: Circulation, Vol. 116, Issue 11 Suppl, pp. I55-63, (2007) (PubMed).

Kuorilehto, Ekholm, Nissinen, Hietaniemi, Hiltunen, Paavolainen, Penttinen, Peltonen: "NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 363-70, (2006) (PubMed).

Hisaoka, Hashimoto, Ohguri, Aoki, Okamoto, Tanaka, Okimoto, Nakamura, Ishida: "Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasia." dans: Skeletal radiology, Vol. 33, Issue 9, pp. 545-9, (2004) (PubMed).

Zou, Butcher, Sadikovic, Groves, Yee, Rodenhiser: "Characterization of functional elements in the neurofibromatosis (NF1) proximal promoter region." dans: Oncogene, Vol. 23, Issue 2, pp. 330-9, (2004) (PubMed).

Zhu, Saberwal, Lu, Platanias, Eklund: "The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1." dans: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50874-85, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à Neurofibromin 1

neurofibromin 1 (NF1), neurofibromin 1 (Nf1), Neurofibromin 1 (Nf1), neurofibromin 1a (nf1a), neurofibromin (LOC593418), neurofibromin (LOC5570549), neurofibromin (CpipJ_CPIJ011774), putative neurofibromin (Smp_148460), AW494271, CG8318, Dmel\\CG8318, dNF1, E030030H24Rik, fe06d03, hm:zehn0874, NF-1, Nf-1, NF1, nf1, NFNS, VRNF, WSS, wu:fe06d03, zehn0874

Protein level used designations for Neurofibromin 1

  • neurofibromatosis-related protein NF-1
  • neurofibromin
  • Neurofibromatosis type 1
  • neurofibromatosis 1
  • CG8318-PB
  • CG8318-PC
  • CG8318-PD
  • CG8318-PE
  • CG8318-PF
  • Neurofibromatosis-1
  • Nf1-PB
  • Nf1-PC
  • Nf1-PD
  • Nf1-PE
  • Nf1-PF
  • neurofibramatosis-1
  • neurofibromatosis factor 1
  • neurofibromatosis type 1
  • neurofibromin 1
  • neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
  • neurofibromin-like
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