NFASC Produits
(Neurofascin (NFASC))
Catégories
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009].
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Catégories NFASC en vedette
NFASC Anticorps
High quality antibodies with extensive validation data.
NFASC Kits ELISA
Reliable ELISA kits for a wide range of species.
NFASC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NFASC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
- (4)
N° du produit
ABIN727325
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
N° du produit
ABIN3017267
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN524981
Quantité
50 μL
Fiche technique
Fiche technique
NFASC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958098
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN2748418
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1144672
Quantité
96 tests
Fiche technique
Fiche technique
NFASC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7197149
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312436
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7386194
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NFASC
: "Neurofilament light chain level is a weak risk factor for the development of MS. ..." dans: Neurology, Vol. 87, Issue 11, pp. 1076-84, (2016) (PubMed).: "Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures." dans: ASN neuro, Vol. 6, Issue 1, pp. e00135, (2014) (PubMed).
: "Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments." dans: The Journal of cell biology, Vol. 205, Issue 1, pp. 67-81, (2014) (PubMed).
: "I?B? is not required for axon initial segment assembly." dans: Molecular and cellular neurosciences, Vol. 50, Issue 1, pp. 1-9, (2012) (PubMed).
: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." dans: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).
: "A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly." dans: Cell, Vol. 149, Issue 5, pp. 1125-39, (2012) (PubMed).
: "Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7439-53, (2012) (PubMed).
: "High-capacity peptide-centric platform to decode the proteomic response to brain injury." dans: Electrophoresis, Vol. 33, Issue 24, pp. 3712-9, (2012) (PubMed).
: "Acrolein induces myelin damage in mammalian spinal cord." dans: Journal of neurochemistry, Vol. 117, Issue 3, pp. 554-64, (2011) (PubMed).
: "Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas." dans: Molecular pain, Vol. 7, pp. 58, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à NFASC
neurofascin (NFASC), neurofascin homolog (chicken) a (nfasca), neurofascin (Nfasc), AA387016, D430023G06Rik, mKIAA0756, NF, NRCAML, sc:d0205Protein level used designations for NFASC
- neurofascin
- neurofascin homolog
- neurofascin homolog (chicken)
- neurofascin-like
- neurofascin homolog (chicken) isoform 1
- neurofascin homolog (chicken) isoform 2
- neurofascin homolog (chicken) isoform 3
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- Neurotrophin Receptor 2
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- Neurotrophin 7
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