NFAT1 Produits
(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
Catégories
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012].
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Catégories NFAT1 en vedette
NFAT1 Anticorps
High quality antibodies with extensive validation data.
NFAT1 Kits ELISA
Reliable ELISA kits for a wide range of species.
NFAT1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NFAT1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (2)
N° du produit
ABIN6972419
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN571020
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
N° du produit
ABIN6748576
Quantité
100 μL
Fiche technique
Fiche technique
NFAT1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6958239
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5657453
Quantité
96 tests
Fiche technique
Fiche technique
NFAT1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312443
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7409788
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094115
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NFAT1
: "The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease." dans: Pediatric rheumatology online journal, Vol. 18, Issue 1, pp. 23, (2020) (PubMed).: "STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension." dans: Hypertension (Dallas, Tex. : 1979), Vol. 71, Issue 3, pp. 518-529, (2018) (PubMed).
: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." dans: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).
: "NFATc2 is an intrinsic regulator of melanoma dedifferentiation." dans: Oncogene, Vol. 35, Issue 22, pp. 2862-72, (2016) (PubMed).
: "Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension." dans: Experimental and therapeutic medicine, Vol. 11, Issue 2, pp. 467-475, (2016) (PubMed).
: "The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells." dans: Cell death & disease, Vol. 6, pp. e1658, (2015) (PubMed).
: "Galanin modulates the neural niche to favour perineural invasion in head and neck cancer." dans: Nature communications, Vol. 6, pp. 6885, (2015) (PubMed).
: "Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat." dans: Circulation research, Vol. 116, Issue 10, pp. 1680-90, (2015) (PubMed).
: "NFAT targets signaling molecules to gene promoters in pancreatic β-cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 2, pp. 274-88, (2015) (PubMed).
: "Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein." dans: Journal of virology, Vol. 88, Issue 21, pp. 12452-63, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à NFAT1
nuclear factor of activated T-cells 2 (NFATC2), nuclear factor of activated T-cells 2 (nfatc2), nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2), nuclear factor of activated T-cells 2 (Nfatc2), AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, Nfatp, NFATPProtein level used designations for NFAT1
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- nuclear factor of activated T-cells, cytoplasmic 2-like
- NF-ATp
- NFAT pre-existing subunit
- T-cell transcription factor NFAT1
- nuclear factor of activated T-cells, cytoplasmic 2
- NF-ATc2
- NFAT transcription complex, preexisting component
- T cell transcription factor NFAT1
- nuclear factor of activated T-cells, preexisting component
- preexisting nuclear factor of activated T-cells 2
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