NHEJ1 Produits
(Nonhomologous End-Joining Factor 1 (NHEJ1))
Catégories
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008].
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Catégories NHEJ1 en vedette
NHEJ1 Anticorps
High quality antibodies with extensive validation data.
NHEJ1 Kits ELISA
Reliable ELISA kits for a wide range of species.
NHEJ1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NHEJ1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey
Application
WB, IF, IHC, FACS, IHC (p)
Validations
- (15)
N° du produit
ABIN1499728
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC
Validations
- (5)
N° du produit
ABIN7261171
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC
Validations
- (4)
N° du produit
ABIN2857060
Quantité
100 μL
Fiche technique
Fiche technique
NHEJ1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1145258
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1145259
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1145260
Quantité
96 tests
Fiche technique
Fiche technique
NHEJ1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312543
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN6387017
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2130830
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NHEJ1
: "PHF6 promotes non-homologous end joining and G2 checkpoint recovery." dans: EMBO reports, Vol. 21, Issue 1, pp. e48460, (2020) (PubMed).: "XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining." dans: Nature structural & molecular biology, Vol. 25, Issue 10, pp. 971-980, (2018) (PubMed).
: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." dans: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).
: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).
: "C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin." dans: Biochemical and biophysical research communications, Vol. 439, Issue 2, pp. 173-8, (2013) (PubMed).
: "Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype." dans: Human mutation, Vol. 31, Issue 9, pp. 1059-68, (2010) (PubMed).
: "Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 11, pp. 4518-23, (2007) (PubMed).
: "Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell." dans: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 31937-43, (2007) (PubMed).
: "XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining." dans: Cell, Vol. 124, Issue 2, pp. 301-13, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à NHEJ1
non-homologous end joining factor 1 (NHEJ1), non-homologous end joining factor 1 S homeolog (nhej1.S), non-homologous end joining factor 1 (nhej1), solute carrier family 23 member 3 (SLC23A3), nonhomologous end-joining factor 1 (nhej1), nonhomologous end-joining factor 1 (Nhej1), 1700029B21Rik, cernunnos, NHEJ1, XLF, zgc:85657Protein level used designations for NHEJ1
- nonhomologous end-joining factor 1
- non-homologous end-joining factor 1
- XRCC4-like factor
- protein cernunnos
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