NLRC4 Produits
(NLR Family, CARD Domain Containing 4 (NLRC4))
Catégories
In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM, Mar 2008].
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Catégories NLRC4 en vedette
NLRC4 Anticorps
High quality antibodies with extensive validation data.
NLRC4 Kits ELISA
Reliable ELISA kits for a wide range of species.
NLRC4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NLRC4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
IHC, IF
Validations
- (5)
N° du produit
ABIN7008065
Quantité
60 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, ICC
Validations
- (4)
N° du produit
ABIN5611209
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
N° du produit
ABIN6144657
Quantité
100 μL
Fiche technique
Fiche technique
NLRC4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968953
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962707
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958209
Quantité
96 tests
Fiche technique
Fiche technique
NLRC4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124183
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3094174
Quantité
250 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3135072
Quantité
250 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NLRC4
: "Iraqi propolis increases degradation of IL-1β and NLRC4 by autophagy following Pseudomonas aeruginosa infection." dans: Microbes and infection, Vol. 20, Issue 2, pp. 89-100, (2018) (PubMed).: "Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121525, (2015) (PubMed).
: "Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation." dans: American journal of physiology. Renal physiology, Vol. 306, Issue 3, pp. F299-308, (2014) (PubMed).
: "Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization." dans: Immunity, Vol. 37, Issue 1, pp. 35-47, (2012) (PubMed).
: "A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif." dans: Nature cell biology, Vol. 2, Issue 12, pp. 915-21, (2001) (PubMed).
: "Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2." dans: Gene, Vol. 261, Issue 2, pp. 197-203, (2001) (PubMed).
: "Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1." dans: The Journal of biological chemistry, Vol. 276, Issue 30, pp. 28309-13, (2001) (PubMed).
: "Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis." dans: Biochemical and biophysical research communications, Vol. 284, Issue 1, pp. 77-82, (2001) (PubMed).
: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).
: "Apoptosis. Till death us do part." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à NLRC4
NLR family CARD domain containing 4 (NLRC4), NLR family, CARD domain containing 4 (Nlrc4), 9530011P19Rik, CARD12, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAFProtein level used designations for NLRC4
- caspase recruitment domain protein 12
- NLR family CARD domain-containing protein 4
- ice protease-activating factor
- ipaf
- NLR family, CARD domain containing 4
- CARD, LRR, and NACHT-containing protein
- ICE-protease activating factor
- NOD-like receptor C4
- caspase recruitment domain family, member 12
- caspase recruitment domain-containing protein 12
- nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
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