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NONO Produits

(Non-POU Domain Containing, Octamer-Binding (NONO))

Catégories

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009].

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Catégories NONO en vedette

NONO Anticorps

High quality antibodies with extensive validation data.

NONO Kits ELISA

Reliable ELISA kits for a wide range of species.

NONO Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NONO recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (10)
N° du produit ABIN6144713
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Mouse
Application WB, IHC, IF, IHC (p)
Validations
  • (11)
N° du produit ABIN1491072
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (18)
N° du produit ABIN1491073
Quantité 100 μL
Fiche technique Fiche technique

NONO recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958220
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5657428
Quantité 96 tests
Fiche technique Fiche technique

NONO recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312785
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409494
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094215
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NONO

Wang, Grunseich, Fox, Burdick, Zhu, Ravazian, Hafner, Cheung: "Human proteins that interact with RNA/DNA hybrids." dans: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).

Hashiramoto, Konishi, Murayama, Kawasaki, Yoshida, Tsumiyama, Tanaka, Mizuhara, Shiotsuki, Kitamura, Komai, Kimura, Yagita, Shiozawa, Shiozawa: "A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell." dans: The Journal of biological chemistry, Vol. 293, Issue 6, pp. 1933-1943, (2017) (PubMed).

Lu, Sewer: "p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation." dans: Molecular and cellular biology, Vol. 35, Issue 7, pp. 1223-37, (2015) (PubMed).

Chaoui, Kavo, Baral, Watanabe, Lecerf, Colley, Mendoza-Londono, Pingault, Bondurand: "Subnuclear re-localization of SOX10 and p54NRB correlates with a unique neurological phenotype associated with SOX10 missense mutations." dans: Human molecular genetics, Vol. 24, Issue 17, pp. 4933-47, (2015) (PubMed).

Isabelle, Gagné, Gallouzi, Poirier: "Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation." dans: Journal of cell science, Vol. 125, Issue Pt 19, pp. 4555-66, (2012) (PubMed).

Krietsch, Caron, Gagné, Ethier, Vignard, Vincent, Rouleau, Hendzel, Poirier, Masson: "PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks." dans: Nucleic acids research, Vol. 40, Issue 20, pp. 10287-301, (2012) (PubMed).

Tsofack, Garand, Sereduk, Chow, Aziz, Guay, Yin, Lebel: "NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines." dans: Molecular cancer, Vol. 10, pp. 145, (2011) (PubMed).

Bubenik, Ladd, Gerber, Budiman, Driscoll: "Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2." dans: RNA biology, Vol. 6, Issue 1, pp. 73-83, (2009) (PubMed).

Zhang, Zhang, Shen, Burks, Zhang, Wang, LeMaire, Yoshimura, Aoki, Coselli, Wang: "TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 27, Issue 8, pp. 1760-7, (2007) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à NONO

non-POU domain containing octamer binding (NONO), non-POU domain containing, octamer-binding (NONO), non-POU domain containing, octamer-binding (Nono), non-POU domain containing, octamer binding L homeolog (nono.L), non-POU-domain-containing, octamer binding protein (Nono), AA407051, AV149256, NMT55, nmt55, nonA, NRB54, nrb54, P54, P54NRB, p54nrb, xp54nrb

Protein level used designations for NONO

  • 54 kDa nuclear RNA- and DNA-binding protein
  • 55 kDa nuclear protein
  • DNA-binding p52/p100 complex, 52 kDa subunit
  • non-POU domain-containing octamer (ATGCAAAT) binding protein
  • non-POU domain-containing octamer-binding protein
  • p54(nrb)
  • non-POU-domain-containing, octamer-binding protein
  • 54 kD nuclear RNA-binding protein
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