Notch1 Produits
(Notch 1 (NOTCH1))
Catégories
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories Notch1 en vedette
Notch1 Anticorps
High quality antibodies with extensive validation data.
Notch1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Notch1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Notch1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
FACS
Validations
- (6)
- (4)
N° du produit
ABIN807924
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
FACS
Validations
- (6)
- (4)
N° du produit
ABIN2749161
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN675114
Quantité
100 μL
Fiche technique
Fiche technique
Notch1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958221
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958222
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958223
Quantité
96 tests
Fiche technique
Fiche technique
Notch1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275363
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275364
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320796
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Notch1
: "Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway." dans: Scientific reports, Vol. 10, Issue 1, pp. 5708, (2020) (PubMed).: "Altered expression of Notch1 in Alzheimer's disease." dans: PLoS ONE, Vol. 14, Issue 11, pp. e0224941, (2020) (PubMed).
: "Enhanced lysosomal degradation maintains the quiescent state of neural stem cells." dans: Nature communications, Vol. 10, Issue 1, pp. 5446, (2019) (PubMed).
: "Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling." dans: Cell stem cell, Vol. 23, Issue 4, pp. 530-543.e9, (2018) (PubMed).
: "Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations." dans: Scientific reports, Vol. 8, Issue 1, pp. 17987, (2018) (PubMed).
: "Prognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastases." dans: Clinical oral investigations, (2017) (PubMed).
: "NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis." dans: Stem cells (Dayton, Ohio), Vol. 35, Issue 4, pp. 1106-1119, (2017) (PubMed).
: "Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning." dans: Developmental cell, Vol. 40, Issue 5, pp. 505-511.e6, (2017) (PubMed).
: "Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1." dans: The Journal of biological chemistry, Vol. 292, Issue 2, pp. 732-747, (2017) (PubMed).
: "Chlamydia and ocular adnexal lymphomas: An Indian experience." dans: Experimental and molecular pathology, Vol. 101, Issue 1, pp. 74-80, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à Notch1
notch 1 (notch1), fibropellin-1 (LOC100631526), Notch homolog 1, translocation-associated (Drosophila) (NOTCH1), notch 1 (NOTCH1), Notch homolog 1, translocation-associated (NOTCH1), notch 1 (Notch1), notch 1 S homeolog (notch1.S), 9930111A19Rik, hn1, hN1, lin-12, Mis6, N1, notch, NOTCH, notch-1, notch1, NOTCH1, notch1-a, tan1, TAN1, Tan1, xnotch, xnotch1, xotch, XotchProtein level used designations for Notch1
- notch 1
- Notch homolog 1, translocation-associated (Drosophila)
- Notch homolog 1, translocation-associated
- neurogenic locus notch homolog protein 1
- translocation-associated notch protein TAN-1
- Motch A
- Notch gene homolog 1
- mT14
- major type A protein
- p300
- transmembrane receptor Notch1
- Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila)
- neurogenic locus notch protein homolog
- NOTCH-1
Vous êtes ici:
