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NOTCH3 Produits

(Notch 3 (NOTCH3))
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].

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Catégories NOTCH3 en vedette

NOTCH3 Anticorps

High quality antibodies with extensive validation data.

NOTCH3 Kits ELISA

Reliable ELISA kits for a wide range of species.

NOTCH3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NOTCH3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (7)
N° du produit ABIN7074862
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN390159
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (3)
N° du produit ABIN3023484
Quantité 100 μL
Fiche technique Fiche technique

NOTCH3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968971
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968972
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958226
Quantité 96 tests
Fiche technique Fiche technique

NOTCH3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275361
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275362
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275366
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NOTCH3

Diéguez-Hurtado, Kato, Giaimo, Nieminen-Kelhä, Arf, Ferrante, Bartkuhn, Zimmermann, Bixel, Eilken, Adams, Borggrefe, Vajkoczy, Adams: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." dans: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).

Kato, Diéguez-Hurtado, Park, Hong, Kato-Azuma, Adams, Stehling, Trappmann, Wrana, Koh, Adams: "Pulmonary pericytes regulate lung morphogenesis." dans: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).

Zhang, Dong, Wang, Wang, Chen, Huang: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." dans: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).

Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." dans: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

Zhou, Jiang, Dong, Yan, You, Su, Gong: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." dans: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).

Soylu, Acar, Ozbey, Unal, Koksal, Bassorgun, Ciftcioglu, Ustunel: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).

Ehret, Vogler, Pojar, Elliott, Bradke, Steiner, Kempermann: "Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis." dans: Neurobiology of disease, Vol. 75, pp. 131-41, (2015) (PubMed).

Rusanescu, Mao: "Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 10, pp. 2103-16, (2014) (PubMed).

Soriani, Iannitto, Ricci, Fionda, Malgarini, Morrone, Peruzzi, Ricciardi, Petrucci, Cippitelli, Santoni: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).

Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." dans: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à NOTCH3

notch 3 (NOTCH3), notch 3 (Notch3), notch 3 (notch3), AW229011, CADASIL, CASIL, fa14b08, hpbk, IMF2, N3, notch5, wu:fa14b08

Protein level used designations for NOTCH3

  • Notch homolog 3
  • neurogenic locus notch homolog protein 3
  • Notch gene homolog 3
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