NOXA Produits
(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
Catégories
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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Catégories NOXA en vedette
NOXA Anticorps
High quality antibodies with extensive validation data.
NOXA Kits ELISA
Reliable ELISA kits for a wide range of species.
NOXA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NOXA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (5)
N° du produit
ABIN6145810
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
N° du produit
ABIN7193484
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7163088
Quantité
100 μg
Fiche technique
Fiche technique
NOXA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969250
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969249
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Dog
Analytical Method
Validations
N° du produit
ABIN1147675
Quantité
96 tests
Fiche technique
Fiche technique
NOXA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315507
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3130350
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2727491
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NOXA
: "Genome-scale CRISPR screening for potential targets of ginsenoside compound K." dans: Cell death & disease, Vol. 11, Issue 1, pp. 39, (2021) (PubMed).: "HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma." dans: International journal of cancer, Vol. 142, Issue 9, pp. 1926-1937, (2019) (PubMed).
: "Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide." dans: The Prostate, Vol. 79, Issue 11, pp. 1347-1359, (2019) (PubMed).
: "Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia." dans: Cancer research, Vol. 78, Issue 20, pp. 5793-5807, (2018) (PubMed).
: "Mannose impairs tumour growth and enhances chemotherapy." dans: Nature, Vol. 563, Issue 7733, pp. 719-723, (2018) (PubMed).
: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." dans: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, (2017) (PubMed).
: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." dans: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).
: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." dans: Cell death & disease, Vol. 7, pp. e2266, (2016) (PubMed).
: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." dans: Oncogene, (2015) (PubMed).
: "Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner." dans: Gut, Vol. 64, Issue 7, pp. 1040-8, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à NOXA
phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1), phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1), APR, NOXA, Noxa, PMAIP1, TN3, zgc:162379Protein level used designations for NOXA
- phorbol-12-myristate-13-acetate-induced protein 1
- Noxa
- PMA-induced protein 1
- adult T cell leukemia-derived PMA-responsive
- immediate-early-response protein APR
- protein Noxa
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