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NPM1 Produits

(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

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Catégories NPM1 en vedette

NPM1 Anticorps

High quality antibodies with extensive validation data.

NPM1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NPM1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NPM1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
N° du produit ABIN562035
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), IP, FACS
Validations
  • (2)
  • (3)
N° du produit ABIN1737584
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
N° du produit ABIN7435076
Quantité 100 μL
Fiche technique Fiche technique

NPM1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
N° du produit ABIN6574308
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975010
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380488
Quantité 2 x 96 tests
Fiche technique Fiche technique

NPM1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1312882
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124224
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2130870
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NPM1

Glushonkov, Réal, Boutant, Mély, Didier: "Optimized protocol for combined PALM-dSTORM imaging." dans: Scientific reports, Vol. 8, Issue 1, pp. 8749, (2018) (PubMed).

Zhang, Zhao, Zhao, Zhu, Weng, Chen, Sun, Mi, Li, Zhu, Chen, Pandolfi, Chen, Yan, Xu: "Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival." dans: Theranostics, Vol. 8, Issue 16, pp. 4359-4371, (2018) (PubMed).

Jiang, Xie, Cai, Ren, Ma: "Effects of hepatitis C virus core protein and nonstructural protein 4B on the Wnt/β-catenin pathway." dans: BMC microbiology, Vol. 17, Issue 1, pp. 124, (2017) (PubMed).

El Hajj, Dassouki, Berthier, Raffoux, Ades, Legrand, Hleihel, Sahin, Tawil, Salameh, Zibara, Darwiche, Mohty, Dombret, Fenaux, de Thé, Bazarbachi: "Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells." dans: Blood, Vol. 125, Issue 22, pp. 3447-54, (2015) (PubMed).

Cai, Zeng, Xiang, Liu, Zhang, Li, She, Yang, Xia, Peng: "iTRAQ-Based Quantitative Proteomic Analysis of Nasopharyngeal Carcinoma." dans: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1431-41, (2015) (PubMed).

Morgado-Palacin, Llanos, Urbano-Cuadrado, Blanco-Aparicio, Megias, Pastor, Serrano: "Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway." dans: Carcinogenesis, Vol. 35, Issue 12, pp. 2822-30, (2014) (PubMed).

Röwer, Ziems, Radtke, Schmitt, Reimer, Koy, Thiesen, Gerber, Glocker: "Toponostics of invasive ductal breast carcinoma: combination of spatial protein expression imaging and quantitative proteome signature analysis." dans: International journal of clinical and experimental pathology, Vol. 4, Issue 5, pp. 454-67, (2011) (PubMed).

ODwyer, Ralton, OShea, Murray: "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27718, (2011) (PubMed).

Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." dans: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

Taylor, Gercel-Taylor, Parker: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." dans: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à NPM1

nucleophosmin 1 (NPM1), nucleophosmin 1 (Npm1), nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog (npm1.L), nucleophosmin 1b (npm1b), Nucleophosmin (npm), nucleophosmin (NPM1), nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), Nucleoplasmin (Nlp), nucleophosmin 1a (npm1a), B23, B23NP, CG7917, CRP1, Crp1, Dmel\\CG7917, dNLP, dNLP-S, NO38, NPM, Npm, npm, npm1, npm4, p22, sb:cb487

Protein level used designations for NPM1

  • nucleolar protein NO38
  • nucleophosmin
  • nucleophosmin/nucleoplasmin family, member 1
  • nucleolar phosphoprotein B23
  • numatrin
  • NPM
  • nucleolar protein B23.1
  • nucleophosmin 1
  • nucleoplasmin
  • nucleophosmin/nucleoplasmin, 4
  • Nucleophosmin
  • CG7917-PA
  • CG7917-PB
  • Nlp-PA
  • Nlp-PB
  • Nucleoplasmin-like
  • chromatin decondensation protein 1
  • nucleoplasmin-1
  • nucleophosmin 1a (nucleolar phosphoprotein B23, numatrin)
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