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NPTX2 Produits

(Neuronal Pentraxin II (NPTX2))

Catégories

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009].

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Catégories NPTX2 en vedette

NPTX2 Anticorps

High quality antibodies with extensive validation data.

NPTX2 Kits ELISA

Reliable ELISA kits for a wide range of species.

NPTX2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NPTX2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN6242482
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN389175
Quantité 400 μL
Fiche technique Fiche technique

Application WB
Validations
  • (2)
  • (1)
N° du produit ABIN6746446
Quantité 100 μL
Fiche technique Fiche technique

NPTX2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958131
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958132
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958133
Quantité 96 tests
Fiche technique Fiche technique

NPTX2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312904
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7410661
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7389926
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NPTX2

Goetzl, Abner, Jicha, Kapogiannis, Schwartz: "Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 2, pp. 888-893, (2018) (PubMed).

Shukla, Pia Patric, Thinagararjan, Srinivasan, Mondal, Hegde, Chandramouli, Santosh, Arivazhagan, Somasundaram: "A DNA methylation prognostic signature of glioblastoma: identification of NPTX2-PTEN-NF-κB nexus." dans: Cancer research, Vol. 73, Issue 22, pp. 6563-73, (2013) (PubMed).

Moran, Hickey, Michael, Derkacs, Christian, Kalaitzakis, Pearce, Graeber: "Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies." dans: Acta neuropathologica, Vol. 115, Issue 4, pp. 471-8, (2008) (PubMed).

Marui, Koishi, Funatogawa, Yamamoto, Matsumoto, Hashimoto, Ishijima, Nanba, Nishida, Sugiyama, Kasai, Watanabe, Kano, Kato, Sasaki: "No association between the neuronal pentraxin II gene polymorphism and autism." dans: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 31, Issue 4, pp. 940-3, (2007) (PubMed).

Park, Ryu, Lee, Lee, Yoon, Lee, Yoo, Woo, Lee, Lee, Kim, Yoon: "Quantitative analysis of NPTX2 hypermethylation is a promising molecular diagnostic marker for pancreatic cancer." dans: Pancreas, Vol. 35, Issue 3, pp. e9-15, (2007) (PubMed).

Xu, Hopf, Reddy, Cho, Guo, Lanahan, Petralia, Wenthold, OBrien, Worley: "Narp and NP1 form heterocomplexes that function in developmental and activity-dependent synaptic plasticity." dans: Neuron, Vol. 39, Issue 3, pp. 513-28, (2003) (PubMed).

Wong, Setou, Teng, Takei, Hirokawa: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).

Biederer, Südhof: "Mints as adaptors. Direct binding to neurexins and recruitment of munc18." dans: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39803-6, (2001) (PubMed).

Kirkpatrick, Matzuk, Dodds, Perin: "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2." dans: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17786-92, (2000) (PubMed).

Tsui, Copeland, Gilbert, Jenkins, Barnes, Worley: "Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2463-78, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à NPTX2

neuronal pentraxin 2 (NPTX2), neuronal pentraxin 2 (Nptx2), neuronal pentraxin II (NPTX2), neuronal pentraxin 1 (NPTX1), neuronal pentraxin 2a (nptx2a), NARP, Narp, NP-II, NP2, np2, NPTX2, nptx2, p50

Protein level used designations for NPTX2

  • apexin
  • neuronal activity-regulated pentaxin
  • neuronal pentraxin-2
  • NP-II
  • neuro activity regulated petaxin
  • neuronal pentraxin II
  • NP2
  • neuronal activity-regulated pentraxin
  • neuronal pentraxin 2
  • AM50
  • acrosomal pentaxin-like protein p50
  • narp
  • neuronal pentraxin 2a
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