NR0B2 Produits
(Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
Catégories
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008].
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Catégories NR0B2 en vedette
NR0B2 Anticorps
High quality antibodies with extensive validation data.
NR0B2 Kits ELISA
Reliable ELISA kits for a wide range of species.
NR0B2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NR0B2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (5)
N° du produit
ABIN3015601
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
N° du produit
ABIN655027
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Monkey, Rabbit
Application
WB, IHC, IHC (p)
Validations
- (4)
N° du produit
ABIN6741607
Quantité
100 μL
Fiche technique
Fiche technique
NR0B2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958250
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative
Validations
N° du produit
ABIN627370
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Dog
Analytical Method
Quantitative
Validations
N° du produit
ABIN995938
Quantité
96 tests
Fiche technique
Fiche technique
NR0B2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312927
Quantité
2 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413040
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418809
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NR0B2
: "Bile acid malabsorption is associated with diarrhea in acute phase of colitis." dans: Canadian journal of physiology and pharmacology, Vol. 96, Issue 12, pp. 1328-1336, (2019) (PubMed).: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." dans: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).
: "The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3)." dans: Molecular pharmacology, Vol. 82, Issue 5, pp. 918-28, (2012) (PubMed).
: "Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth." dans: Gastroenterology, Vol. 134, Issue 3, pp. 793-802, (2008) (PubMed).
: "Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model." dans: Carcinogenesis, Vol. 29, Issue 11, pp. 2218-26, (2008) (PubMed).
: "Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well ..." dans: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 10, pp. 2326-42, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à NR0B2
nuclear receptor subfamily 0 group B member 2 (NR0B2), nuclear receptor subfamily 0, group B, member 2 (Nr0b2), nuclear receptor subfamily 0, group B, member 2a (nr0b2a), gb:bc058069, Nr0b2, NR0B2-A, SHP, Shp, SHP-1, SHP-A, SHP1, Shp1Protein level used designations for NR0B2
- short heterodimer partner
- nuclear receptor subfamily 0 group B member 2
- nuclear receptor SHP
- orphan nuclear receptor SHP
- small heterodimer partner
- small heterodimer partner homologue
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