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NR0B2 Produits

(Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))

Catégories

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008].

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Catégories NR0B2 en vedette

NR0B2 Anticorps

High quality antibodies with extensive validation data.

NR0B2 Kits ELISA

Reliable ELISA kits for a wide range of species.

NR0B2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NR0B2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (5)
N° du produit ABIN3015601
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
N° du produit ABIN655027
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (4)
N° du produit ABIN6741607
Quantité 100 μL
Fiche technique Fiche technique

NR0B2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958250
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative
Validations
N° du produit ABIN627370
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Dog
Analytical Method Quantitative
Validations
N° du produit ABIN995938
Quantité 96 tests
Fiche technique Fiche technique

NR0B2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312927
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413040
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418809
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NR0B2

Hou, Fan, Liu, Cheng, Chang, Wu, Shao: "Bile acid malabsorption is associated with diarrhea in acute phase of colitis." dans: Canadian journal of physiology and pharmacology, Vol. 96, Issue 12, pp. 1328-1336, (2019) (PubMed).

Fotschki, Juśkiewicz, Jurgoński, Rigby, Sójka, Kołodziejczyk, Mackie, Zduńczyk: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." dans: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).

Laurenzana, Chen, Kannuswamy, Sell, Strom, Li, Omiecinski: "The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3)." dans: Molecular pharmacology, Vol. 82, Issue 5, pp. 918-28, (2012) (PubMed).

He, Park, Zhang, Huang, Lu, Wang: "Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth." dans: Gastroenterology, Vol. 134, Issue 3, pp. 793-802, (2008) (PubMed).

Takahashi, Shibutani, Woo, Inoue, Fujimoto, Igarashi, Kanno, Hirose, Nishikawa: "Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model." dans: Carcinogenesis, Vol. 29, Issue 11, pp. 2218-26, (2008) (PubMed).

Iyer, Zhang, McCabe et al.: "Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well ..." dans: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 10, pp. 2326-42, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à NR0B2

nuclear receptor subfamily 0 group B member 2 (NR0B2), nuclear receptor subfamily 0, group B, member 2 (Nr0b2), nuclear receptor subfamily 0, group B, member 2a (nr0b2a), gb:bc058069, Nr0b2, NR0B2-A, SHP, Shp, SHP-1, SHP-A, SHP1, Shp1

Protein level used designations for NR0B2

  • short heterodimer partner
  • nuclear receptor subfamily 0 group B member 2
  • nuclear receptor SHP
  • orphan nuclear receptor SHP
  • small heterodimer partner
  • small heterodimer partner homologue
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