NR1H2 Produits
(Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
Catégories
The liver X receptors, LXRA (NR1H3\; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs\; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].
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Catégories NR1H2 en vedette
NR1H2 Anticorps
High quality antibodies with extensive validation data.
NR1H2 Kits ELISA
Reliable ELISA kits for a wide range of species.
NR1H2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NR1H2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (7)
N° du produit
ABIN7444937
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN521265
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (4)
N° du produit
ABIN185293
Quantité
100 μg
Fiche technique
Fiche technique
NR1H2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969009
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN579470
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN454778
Quantité
96 tests
Fiche technique
Fiche technique
NR1H2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312932
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7420831
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7419373
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NR1H2
: "Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation." dans: Genome medicine, Vol. 8, Issue 1, pp. 74, (2016) (PubMed).: "Complementary Cholesterol-Lowering Response of a Phytosterol/?-Lipoic Acid Combination in Obese Zucker Rats." dans: Journal of dietary supplements, (2015) (PubMed).
: "Effect of garlic on lipid profile and expression of LXR alpha in intestine and liver of hypercholesterolemic mice." dans: Journal of diabetes and metabolic disorders, Vol. 13, Issue 1, pp. 20, (2014) (PubMed).
: "Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation." dans: Cell, Vol. 156, Issue 5, pp. 986-1001, (2014) (PubMed).
: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." dans: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).
: "The probiotic Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum NR74 promote cholesterol efflux and suppress inflammation in THP-1 cells." dans: Journal of the science of food and agriculture, Vol. 93, Issue 4, pp. 781-7, (2013) (PubMed).
: "Reduction in cholesterol absorption in Caco-2 cells through the down-regulation of Niemann-Pick C1-like 1 by the putative probiotic strains Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum ..." dans: International journal of food sciences and nutrition, Vol. 64, Issue 1, pp. 44-52, (2013) (PubMed).
: "Lipocalin 2 deficiency alters estradiol production and estrogen receptor signaling in female mice." dans: Endocrinology, Vol. 153, Issue 3, pp. 1183-93, (2012) (PubMed).
: "Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors." dans: Placenta, Vol. 32, Issue 2, pp. 183-91, (2011) (PubMed).
: "Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease." dans: PLoS ONE, Vol. 6, Issue 8, pp. e24293, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à NR1H2
nuclear receptor subfamily 1 group H member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 (nr1h2), nuclear receptor subfamily 1, group H, member 2 (Nr1h2), nuclear receptor subfamily 1, group H, member 2 (NR1H2), nuclear receptor subfamily 1 group H member 2 L homeolog (nr1h2.L), AI194859, DKFZp468A0622, LXR, lxr-b, LXR-b, lxrb, LXRB, LXRbeta, ner, NER, ner-i, NER-I, NER1, NR1H2, OR-1, rip15, RIP15, unr, Unr, UNR, Unr2, URProtein level used designations for NR1H2
- nuclear receptor subfamily 1, group H, member 2
- LXR beta
- liver X receptor beta
- oxysterols receptor LXR-beta
- retinoid X receptor-interacting protein No.15
- ubiquitously-expressed nuclear receptor 2
- UR
- nuclear orphan receptor LXR-beta
- orphan nuclear receptor OR-1
- ubiquitous receptor
- ubiquitously-expressed nuclear receptor
- LX receptor beta
- liver X nuclear receptor beta
- nuclear receptor NER
- steroid hormone-nuclear receptor NER
- nuclear receptor subfamily 1 group H member 2
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