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NR1H4 Produits

(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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Catégories NR1H4 en vedette

NR1H4 Anticorps

High quality antibodies with extensive validation data.

NR1H4 Kits ELISA

Reliable ELISA kits for a wide range of species.

NR1H4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NR1H4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7440740
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
  • (4)
N° du produit ABIN523347
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
N° du produit ABIN2778066
Quantité 100 μL
Fiche technique Fiche technique

NR1H4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958257
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969011
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958255
Quantité 96 tests
Fiche technique Fiche technique

NR1H4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312937
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312936
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412779
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NR1H4

Kanasaki, Iida, Murao, Shirouchi, Sato: "D-Allulose enhances uptake of HDL-cholesterol into rat's primary hepatocyte via SR-B1." dans: Cytotechnology, Vol. 72, Issue 2, pp. 295-301, (2020) (PubMed).

Zhao, Liu, Cheng, Xiao, Hu, Tang, Bao, Yang, Jiang, Hu, Gonzalez, Li: "Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling." dans: Molecular & cellular proteomics : MCP, Vol. 18, Issue 3, pp. 520-533, (2019) (PubMed).

Zhao, Elhafiz, Jiang, Das, Li, Zhou, Fan, Wang, Yuan, Xu, Jiang, Zhang, Wang: "Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity." dans: Toxicology and applied pharmacology, Vol. 362, pp. 150-158, (2019) (PubMed).

Yang, Mei, Xu, Zhou, Zhu, Sun, Huang, Wang, Shu, Liu, Ding, Hassan, Zhang, Jiang: "Early indications of ANIT-induced cholestatic liver injury: Alteration of hepatocyte polarization and bile acid homeostasis." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 110, pp. 1-12, (2018) (PubMed).

Zhang, Hwang, Oh, Park, Chung, Lee, Baek, Ryoo, Woo: "Effects of the fibrous topography-mediated macrophage phenotype transition on the recruitment of mesenchymal stem cells: An in vivo study." dans: Biomaterials, Vol. 149, pp. 77-87, (2018) (PubMed).

Gallo-Ebert, Francisco, Liu, Draper, Modi, Hayward, Jones, Buiakova, McDonough, Nickels: "Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease." dans: The Journal of biological chemistry, Vol. 293, Issue 16, pp. 5956-5974, (2018) (PubMed).

Malivindi, Santoro, De Rose, Panza, Gervasi, Rago, Aquila: "Activated-farnesoid X receptor (FXR) expressed in human sperm alters its fertilising ability." dans: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 249-259, (2018) (PubMed).

Fotschki, Juśkiewicz, Jurgoński, Rigby, Sójka, Kołodziejczyk, Mackie, Zduńczyk: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." dans: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).

Yu, Liu, Yuan, Li, Yang, Yuan, Sun, Zhang, Jiang: "SRT1720 Alleviates ANIT-Induced Cholestasis in a Mouse Model." dans: Frontiers in pharmacology, Vol. 8, pp. 256, (2017) (PubMed).

Lian, Wang, Xiao, Wu, Xu, Liang, Yang: "Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis." dans: Molecular medicine reports, Vol. 12, Issue 4, pp. 5821-7, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à NR1H4

nuclear receptor subfamily 1, group H, member 5 S homeolog (nr1h5.S), nuclear receptor subfamily 1, group H, member 4 (nr1h4), nuclear receptor subfamily 1 group H member 4 (NR1H4), nuclear receptor subfamily 1, group H, member 4 (Nr1h4), AI957360, BAR, FXR, Fxr, HRR-1, HRR1, NR1H4, RIP14, Rxrip14, zgc:92742, zgc:110190

Protein level used designations for NR1H4

  • nuclear receptor subfamily 1, group H, member 4
  • orphan nuclear receptor FOR2
  • FXRalpha
  • bile acid receptor
  • farnesoid X activated receptor
  • bile acid receptor-like
  • RXR-interacting protein 14
  • farnesoid X nuclear receptor
  • farnesoid X-activated receptor
  • farnesol receptor HRR-1
  • retinoid X receptor-interacting protein 14
  • nuclear receptor subfamily 1 group H member 4
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