NR1I3 Produits
(Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
Catégories
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories NR1I3 en vedette
NR1I3 Anticorps
High quality antibodies with extensive validation data.
NR1I3 Kits ELISA
Reliable ELISA kits for a wide range of species.
NR1I3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NR1I3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (5)
N° du produit
ABIN7259546
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (3)
N° du produit
ABIN7161898
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN462245
Quantité
50 μg
Fiche technique
Fiche technique
NR1I3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969015
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969014
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969016
Quantité
96 tests
Fiche technique
Fiche technique
NR1I3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312943
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312942
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418869
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NR1I3
: "Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine." dans: British journal of pharmacology, Vol. 172, Issue 5, pp. 1263-76, (2015) (PubMed).Synonymes et noms alternatifs relatifs à NR1I3
nuclear receptor subfamily 1 group I member 3 (NR1I3), nuclear receptor subfamily 1, group I, member 3 (Nr1i3), AA209988, AI551208, CAR, CAR-beta, CAR1, Care2, CXR, ESTM32, MB67Protein level used designations for NR1I3
- constitutive androstane receptor
- constitutively transactivates RAREs
- nuclear receptor subfamily 1 group I member 3
- orphan nuclear receptor MB67
- constitutive androstane receptor NR1I3
- nuclear receptor constitutive active receptor
- strain Fischer nuclear receptor (CAR)
- constitutive activator of retinoid response
- constitutive active receptor
- constitutive active response
- constitutive androstane nuclear receptor variant 2
- constitutive androstane nuclear receptor variant 3
- constitutive androstane nuclear receptor variant 4
- constitutive androstane nuclear receptor variant 5
- orphan nuclear hormone receptor
- xenobiotic receptor
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