Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

NR1I3 Produits

(Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Catégories

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories NR1I3 en vedette

NR1I3 Anticorps

High quality antibodies with extensive validation data.

NR1I3 Kits ELISA

Reliable ELISA kits for a wide range of species.

NR1I3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NR1I3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
N° du produit ABIN7259546
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
N° du produit ABIN7161898
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN462245
Quantité 50 μg
Fiche technique Fiche technique

NR1I3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969015
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969014
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969016
Quantité 96 tests
Fiche technique Fiche technique

NR1I3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312943
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312942
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418869
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NR1I3

Sharma, Lau, Sherman, Chang: "Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine." dans: British journal of pharmacology, Vol. 172, Issue 5, pp. 1263-76, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à NR1I3

nuclear receptor subfamily 1 group I member 3 (NR1I3), nuclear receptor subfamily 1, group I, member 3 (Nr1i3), AA209988, AI551208, CAR, CAR-beta, CAR1, Care2, CXR, ESTM32, MB67

Protein level used designations for NR1I3

  • constitutive androstane receptor
  • constitutively transactivates RAREs
  • nuclear receptor subfamily 1 group I member 3
  • orphan nuclear receptor MB67
  • constitutive androstane receptor NR1I3
  • nuclear receptor constitutive active receptor
  • strain Fischer nuclear receptor (CAR)
  • constitutive activator of retinoid response
  • constitutive active receptor
  • constitutive active response
  • constitutive androstane nuclear receptor variant 2
  • constitutive androstane nuclear receptor variant 3
  • constitutive androstane nuclear receptor variant 4
  • constitutive androstane nuclear receptor variant 5
  • orphan nuclear hormone receptor
  • xenobiotic receptor
Vous êtes ici:
Support technique