NSMCE2 Produits
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
Catégories
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
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Catégories NSMCE2 en vedette
NSMCE2 Anticorps
High quality antibodies with extensive validation data.
NSMCE2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NSMCE2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
- (2)
N° du produit
ABIN531598
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
N° du produit
ABIN7150959
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
N° du produit
ABIN3185961
Quantité
100 μL
Fiche technique
Fiche technique
NSMCE2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313078
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094191
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3136789
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NSMCE2
: "Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress." dans: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).: "Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals." dans: Biomedical and environmental sciences : BES, Vol. 28, Issue 9, pp. 660-5, (2015) (PubMed).
: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." dans: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).
: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." dans: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à NSMCE2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L), Smc5-6 complex non-SMC subunit 2 (nse2), 1110014D18Rik, AI661537, C8orf36, MMS21, Non-SMC element 2, NSE2, RGD1305156, ZMIZ7Protein level used designations for NSMCE2
- E3 SUMO-protein ligase NSE2
- MMS21 homolog
- non-structural maintenance of chromosomes element 2 homolog
- non-SMC element 2 homolog
- hMMS21
- methyl methanesulfonate sensitivity gene 21
- zinc finger, MIZ-type containing 7
- non-SMC element 2 homolog (MMS21, S. cerevisiae)
- Non-structural maintenance of chromosomes element 2
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