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NTAN1 Produits

(N-terminal Asparagine Amidase (NTAN1))

Catégories

The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012].

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Catégories NTAN1 en vedette

NTAN1 Anticorps

High quality antibodies with extensive validation data.

NTAN1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NTAN1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NTAN1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7165837
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7246970
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN1536839
Quantité 400 μL
Fiche technique Fiche technique

NTAN1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5595273
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6234098
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN6200673
Quantité 96 tests
Fiche technique Fiche technique

NTAN1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313099
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2727674
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Pig
Source Yeast
Validations
N° du produit ABIN1621088
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NTAN1

Bahmani, Uehara, Ordikhani, Li, Jiang, Banouni, Ichimura, Kasinath, Eskandari, Annabi, Bromberg, Shultz, Greiner, Abdi: "Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery." dans: EBioMedicine, Vol. 38, pp. 79-88, (2019) (PubMed).

Uehara, Li, Sheikhi, Zandi, Walker, Saleh, Banouni, Jiang, Ordikhani, Dai, Yonar, Vohra, Kasinath, Orgill, Khademhosseini, Annabi, Abdi: "Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival." dans: Scientific reports, Vol. 9, Issue 1, pp. 6535, (2019) (PubMed).

Matsubara, Seki, Suzuki, Komori, Takamori: "Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors." dans: Journal for immunotherapy of cancer, Vol. 7, Issue 1, pp. 256, (2019) (PubMed).

Bahmani, Uehara, Jiang, Ordikhani, Banouni, Ichimura, Solhjou, Furtmüller, Brandacher, Alvarez, von Andrian, Uchimura, Xu, Vohra, Yilmam, Haik, Azzi, Kasinath, Bromberg, McGrath, Abdi: "Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival." dans: The Journal of clinical investigation, Vol. 128, Issue 11, pp. 4770-4786, (2018) (PubMed).

Jentho, Bodden, Schulz, Jung, Seidel, Schmeck, Bertrams: "microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0176204, (2017) (PubMed).

Hautz, Zelger, Nasr, Mundinger, Barth, Rodriguez, Brandacher, Weissenbacher, Zelger, Cavadas, Margreiter, Lee, Pratschke, Lakkis, Schneeberger: "Lymphoid neogenesis in skin of human hand, nonhuman primate, and rat vascularized composite allografts." dans: Transplant international : official journal of the European Society for Organ Transplantation, Vol. 27, Issue 9, pp. 966-76, (2014) (PubMed).

Hirakawa, Tsuboi, Sato, Kobayashi, Watanabe, Takakura, Imai, Ito, Fukuda, Kawashima: "Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing." dans: The Journal of biological chemistry, Vol. 285, Issue 52, pp. 40864-78, (2010) (PubMed).

Burke, Dong, Hazan, Croy: "Aberrant endometrial features of pregnancy in diabetic NOD mice." dans: Diabetes, Vol. 56, Issue 12, pp. 2919-26, (2007) (PubMed).

Drayton, Ying, Lee, Lesslauer, Ruddle: "Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase." dans: The Journal of experimental medicine, Vol. 197, Issue 9, pp. 1153-63, (2003) (PubMed).

Samulowitz, Kuhn, Brachtendorf, Nawroth, Braun, Bankfalvi, Böcker, Vestweber: "Human endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitope." dans: The American journal of pathology, Vol. 160, Issue 5, pp. 1669-81, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à NTAN1

N-terminal Asn amidase (Ntan1), N-terminal asparagine amidase (NTAN1), PNAA, PNAD

Protein level used designations for NTAN1

  • N-terminal asparagine amidohydrolase
  • PNAA
  • PNAD
  • asparagine-specific N-terminal amidase
  • protein N-terminal Asn amidase
  • protein N-terminal asparagine amidohydrolase
  • protein NH2-terminal asparagine amidohydrolase
  • protein NH2-terminal asparagine deamidase
  • protein NTN-amidase
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