NUMB Produits
(Numb Homolog (NUMB))
Catégories
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories NUMB en vedette
NUMB Anticorps
High quality antibodies with extensive validation data.
NUMB Kits ELISA
Reliable ELISA kits for a wide range of species.
NUMB Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NUMB recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN6144943
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC, IF, FACS
Validations
- (9)
N° du produit
ABIN184679
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN563731
Quantité
100 μg
Fiche technique
Fiche technique
NUMB recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4884024
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385253
Quantité
96 tests
Fiche technique
Fiche technique
NUMB recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313212
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405789
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405792
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NUMB
: "Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer." dans: Cell, Vol. 178, Issue 1, pp. 135-151.e19, (2019) (PubMed).: "Effect of experimentally induced hypothyroidism during gestation period on activity dependent neurotrophic factor (ADNF) in newborn rat brain tissue." dans: Hormone molecular biology and clinical investigation, Vol. 36, Issue 3, (2018) (PubMed).
: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." dans: Molecular neurobiology, (2016) (PubMed).
: "Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway." dans: Stem cell reports, Vol. 5, Issue 5, pp. 866-80, (2015) (PubMed).
: "Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy." dans: Journal of physiology and biochemistry, Vol. 71, Issue 2, pp. 217-26, (2015) (PubMed).
: "The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1." dans: Nature medicine, Vol. 20, Issue 1, pp. 80-6, (2014) (PubMed).
: "NUMB controls p53 tumour suppressor activity." dans: Nature, Vol. 451, Issue 7174, pp. 76-80, (2008) (PubMed).
: "Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas." dans: International journal of immunopathology and pharmacology, Vol. 20, Issue 4, pp. 779-89, (2008) (PubMed).
: "Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3." dans: Developmental cell, Vol. 13, Issue 1, pp. 15-28, (2007) (PubMed).
: "Asymmetric localization of numb in the chick somite and the influence of myogenic signals." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 235, Issue 3, pp. 633-45, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à NUMB
NUMB, endocytic adaptor protein (NUMB), numb homolog (Drosophila) (Numb), NUMB, endocytic adaptor protein (Numb), numb homolog (Drosophila) (numb), C14orf41, c14_5527, Nb, S171Protein level used designations for NUMB
- h-Numb
- protein numb homolog
- numb gene homolog
- numb homolog
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