NUP98 Produits
(Nucleoporin 98kDa (NUP98))
Catégories
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, May 2010].
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Catégories NUP98 en vedette
NUP98 Anticorps
High quality antibodies with extensive validation data.
NUP98 Kits ELISA
Reliable ELISA kits for a wide range of species.
NUP98 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NUP98 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe
Application
WB, ELISA, IF, ICC, DB
Validations
- (2)
- (14)
N° du produit
ABIN2452066
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
Application
WB, IF
Validations
- (2)
- (8)
N° du produit
ABIN2452064
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
Application
WB, IF
Validations
- (2)
- (8)
N° du produit
ABIN2452065
Quantité
100 μg
Fiche technique
Fiche technique
NUP98 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1116273
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN511450
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN512355
Quantité
96 tests
Fiche technique
Fiche technique
NUP98 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313246
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313248
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7406317
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NUP98
: "NPHP proteins are binding partners of nucleoporins at the base of the primary cilium." dans: PLoS ONE, Vol. 14, Issue 9, pp. e0222924, (2019) (PubMed).: "Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia." dans: Nature, Vol. 561, Issue 7721, pp. 127-131, (2018) (PubMed).
: "Tpr regulates the total number of nuclear pore complexes per cell nucleus." dans: Genes & development, Vol. 32, Issue 19-20, pp. 1321-1331, (2018) (PubMed).
: "Evolution of a transcriptional regulator from a transmembrane nucleoporin." dans: Genes & development, Vol. 30, Issue 10, pp. 1155-71, (2016) (PubMed).
: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).
: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." dans: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à NUP98
Nucleoporin 98-96kD (Nup98-96), nuclear pore complex protein Nup98-Nup96 (LOC408335), nucleoporin 98 (NUP98), nuclear pore complex protein Nup98-Nup96 (LOC587580), nucleoporin 98kDa (NUP98), nucleoporin 98 (Nup98), nucleoporin 98 (nup98), nucleoporin 98 L homeolog (nup98.L), 4732457F17, ADIR2, AI849286, CG10198, CG10201, Dmel\\CG10198, GB12688, im:7151238, l(3)95BCd, Nup-98, Nup 96, Nup96, NUP96, Nup 98, Nup98, NUP98, nup98-96, Nup98-Nup96, Nup98/96, nup145, NUP196, zgc:63593, zgc:113968Protein level used designations for NUP98
- CG10198-PA
- CG10198-PC
- CG10198-PD
- Nup98
- Nup98-96-PA
- Nup98-96-PC
- Nup98-96-PD
- nucleoporin 98
- nucleoporin 98-96
- nucleoporin98-96
- nucleoporin 98kD
- nucleoporin 98kDa
- nuclear pore complex protein Nup98-Nup96-like
- nuclear pore complex protein Nup98-Nup96
- 98 kDa nucleoporin
- nuclear pore complex protein Nup98
- nucleoporin Nup98
- GLFG-repeat containing nucleoporin
- Nup98-Nup96
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