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OAS1A Produits

(2'-5' Oligoadenylate Synthetase 1A (OAS1A))
This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].

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Catégories OAS1A en vedette

OAS1A Anticorps

High quality antibodies with extensive validation data.

OAS1A Kits ELISA

Reliable ELISA kits for a wide range of species.

OAS1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

OAS1A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, ELISA, WB
Validations
N° du produit ABIN1175792
Quantité 200 μL
Fiche technique Fiche technique

OAS1A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6953345
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6953347
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953346
Quantité 96 tests
Fiche technique Fiche technique

OAS1A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3132884
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits OAS1A

Tsujiuchi, Natsume, Motomura, Kondo, Ranjit, Hachisu, Sugimura, Tomita, Takehara, Woolley, Barua, Gill, Bienemann, Yamashita, Toyokuni, Wakabayashi: "Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains." dans: American journal of translational research, Vol. 6, Issue 2, pp. 169-78, (2014) (PubMed).

Bobardt, Hopkins, Baugh, Chatterji, Hernandez, Hiscott, Sluder, Lin, Gallay: "HCV NS5A and IRF9 compete for CypA binding." dans: Journal of hepatology, Vol. 58, Issue 1, pp. 16-23, (2013) (PubMed).

Heyden, Fodor: "Prevention of fatal and nonfatal ischemic heart disease by early treatment of hypertension." dans: Cardiology, Vol. 72 Suppl 1, pp. 182-6, (1985) (PubMed).

Synonymes et noms alternatifs relatifs à OAS1A

2'-5' oligoadenylate synthetase 1A (Oas1a), 2'-5' oligoadenylate synthetase 1B (Oas1b), Flv, L1, L3, Mmu-L1, Oas1, Oas1g, Oias-2, Oias2, Wnv

Protein level used designations for OAS1A

  • (2-5')oligo(A) synthase 1
  • (2-5')oligo(A) synthase 1A
  • (2-5')oligo(A) synthetase 1
  • 2',5'-oligoadenylate synthetase 1, 40/46kDa
  • 2'-5' oligoadenylate synthetase 1G
  • 2'-5'-oligoadenylate synthase 1
  • 2'-5'-oligoadenylate synthase 1A
  • 2'-5'-oligoadenylate synthetase 1
  • 2-5A synthase 1
  • 2-5A synthase 1A
  • 2-5A synthetase 1
  • 25 oligoadenylate synthetase
  • (2-5')oligo(A) synthetase 1A
  • 2-5A synthetase 1A
  • p42 OAS
  • (2-5')oligo(A) synthase 1B
  • (2-5')oligo(A) synthetase 1b
  • 2',5'-oligoadenylate synthetase-like 1
  • 2'-5'-oligoadenylate synthase 1B
  • 2'-5'-oligoadenylate synthase-like protein 1
  • 2'-5'-oligoadenylate synthetase-like protein 1
  • 2-5A synthase 1B
  • 2-5A synthetase 1B
  • Flavivirus resistance
  • inactive 2'-5'-oligoadenylate synthase 1B
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