OGG1 Produits
(8-Oxoguanine DNA Glycosylase (OGG1))
Catégories
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].
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Catégories OGG1 en vedette
OGG1 Anticorps
High quality antibodies with extensive validation data.
OGG1 Kits ELISA
Reliable ELISA kits for a wide range of species.
OGG1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
OGG1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC, ELISA, IP, ICC, IF
Validations
- (7)
N° du produit
ABIN363384
Quantité
0.1 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7435088
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7160762
Quantité
100 μg
Fiche technique
Fiche technique
OGG1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953379
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964509
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964508
Quantité
96 tests
Fiche technique
Fiche technique
OGG1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121628
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667178
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313352
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits OGG1
: "Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats." dans: The Journal of physiology, Vol. 597, Issue 9, pp. 2391-2401, (2019) (PubMed).: "Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 6, pp. 7758-7766, (2019) (PubMed).
: "Levels of oxidative DNA damage are low in ex vivo engineered human limbal epithelial tissue." dans: Acta ophthalmologica, Vol. 96, Issue 8, pp. 834-840, (2019) (PubMed).
: "Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis." dans: Molecular cell, Vol. 75, Issue 1, pp. 117-130.e6, (2019) (PubMed).
: "Knockout of Mpv17-Like Protein (M-LPH) Gene in Human Hepatoma Cells Results in Impairment of mtDNA Integrity through Reduction of TFAM, OGG1, and LIG3 at the Protein Levels." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6956414, (2018) (PubMed).
: "CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells." dans: Nutrients, Vol. 10, Issue 7, (2018) (PubMed).
: "Overexpression of MTH1 and OGG1 proteins in ulcerative colitis-associated carcinogenesis." dans: Oncology letters, Vol. 16, Issue 2, pp. 1765-1776, (2018) (PubMed).
: "The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0164281, (2017) (PubMed).
: "Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice." dans: Oncotarget, Vol. 8, Issue 21, pp. 34082-34098, (2017) (PubMed).
: "The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription." dans: Nucleic acids research, Vol. 46, Issue 2, pp. 661-676, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à OGG1
8-oxoguanine DNA glycosylase (OGG1), 8-oxoguanine DNA glycosylase L homeolog (ogg1.L), 8-oxoguanine DNA glycosylase (ogg1), 8-oxoguanine-DNA glycosylase 1 (OGG1), 8-OXOGUANINE DNA GLYCOSYLASE (ECU08_0770), 8-oxoguanine DNA glycosylase (CA_C2707), 8-oxoguanine DNA glycosylase (BBOV_I004290), putative 8-oxoguanine DNA glycosylase (Smp_074010.1), 8-oxoguanine DNA-glycosylase (ogg1), N-glycosylase/DNA lyase OGG1 (LOC9329243), 8-oxoguanine DNA glycosylase (Tb927.4.2480), 8-oxoguanine DNA glycosylase (Ogg1), 8-oxoguanine DNA-glycosylase 1 (Ogg1), 8-oxoguanine-DNA glycosylase 1, 19.m02329, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, ATOGG1, DDBDRAFT_0184479, DDBDRAFT_0233024, DDB_0184479, DDB_0233024, F8K7.14, F8K7_14, HMMH, HOGG1, Mmh, MUTM, OGG1, ogg1, OGH1, Tb04.1H19.930, zgc:158858Protein level used designations for OGG1
- 8-oxoguanine DNA glycosylase
- N-glycosylase/DNA lyase
- 8-OXOGUANINE DNA GLYCOSYLASE
- 8-oxoguanine-DNA-glycosylase
- DNA-formamidopyrimidine glycosylase
- 8-oxoguanine-DNA glycosylase 1
- 8-oxoguanine DNA-glycosylase 1
- n-glycosylase/DNA lyase-like
- 8-hydroxyguanine DNA glycosylase
- AP lyase
- DNA-apurinic or apyrimidinic site lyase
- OGG1 type 1f
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