ORAI1 Produits
(ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
Catégories
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011].
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Catégories ORAI1 en vedette
ORAI1 Anticorps
High quality antibodies with extensive validation data.
ORAI1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ORAI1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
WB, IHC, FACS, IF, LCI, ICC
Validations
- (6)
N° du produit
ABIN7043408
Quantité
25 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7146306
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (2)
- (1)
N° du produit
ABIN2475964
Quantité
0.1 mg
Fiche technique
Fiche technique
ORAI1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1124739
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1124740
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1124741
Quantité
96 tests
Fiche technique
Fiche technique
ORAI1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3117264
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3125369
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ORAI1
: "Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion." dans: Frontiers in physiology, Vol. 9, pp. 813, (2018) (PubMed).: "Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells." dans: The Journal of biological chemistry, Vol. 291, Issue 40, pp. 21148-21159, (2016) (PubMed).
: "Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression." dans: Cell reports, Vol. 12, Issue 2, pp. 203-16, (2015) (PubMed).
: "Molecular mechanisms of spontaneous and directed mast cell motility." dans: Journal of leukocyte biology, Vol. 92, Issue 5, pp. 1029-41, (2012) (PubMed).
: "Selective activation of the transcription factor NFAT1 by calcium microdomains near Ca2+ release-activated Ca2+ (CRAC) channels." dans: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 14795-803, (2011) (PubMed).
: "POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19234-9, (2011) (PubMed).
: "Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome." dans: Human molecular genetics, Vol. 19, Issue 20, pp. 4026-42, (2010) (PubMed).
: "Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8." dans: Molecular pharmacology, Vol. 75, Issue 4, pp. 830-42, (2009) (PubMed).
: "Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis." dans: Nature cell biology, Vol. 11, Issue 12, pp. 1465-72, (2009) (PubMed).
: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à ORAI1
ORAI calcium release-activated calcium modulator 1 (ORAI1), ORAI calcium release-activated calcium modulator 1 (Orai1), ORAI calcium release-activated calcium modulator 1b (orai1b), ORAI calcium release-activated calcium modulator 1 S homeolog (orai1.S), ORAI calcium release-activated calcium modulator 1 (orai1), CRACM1, D730049H07Rik, im:7146264, LOC100218031, orai-1, orai1, ORAI1, orai2, ORAT1, RGD1311873, TMEM142A, Tmem142a, tmem142a, zgc:109721Protein level used designations for ORAI1
- calcium release-activated calcium channel protein 1
- calcium release-activated calcium modulator 1
- protein orai-1
- transmembrane protein 142A
- calcium release-activated calcium channel 1
- ORAI calcium release-activated calcium modulator 1
- protein orai-2
- transmembrane protein 142B
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