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OSCAR Produits

(Osteoclast Associated Receptor (OSCAR))
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories OSCAR en vedette

OSCAR Anticorps

High quality antibodies with extensive validation data.

OSCAR Kits ELISA

Reliable ELISA kits for a wide range of species.

OSCAR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

OSCAR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN7426541
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN7140032
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN1536842
Quantité 400 μL
Fiche technique Fiche technique

OSCAR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6975614
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6958339
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511453
Quantité 96 tests
Fiche technique Fiche technique

OSCAR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275377
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275378
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313704
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits OSCAR

Zawawi, Marino, Perilli, Cantley, Xu, Purdue, Dharmapatni, Haynes, Crotti: "Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis." dans: Journal of biomedical materials research. Part A, (2015) (PubMed).

Zawawi, Perilli, Stansborough, Marino, Cantley, Xu, Dharmapatni, Haynes, Gibson, Crotti: "Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis." dans: Calcified tissue international, Vol. 96, Issue 6, pp. 565-74, (2015) (PubMed).

Stefanovic, Cukuranovic, Dolicanin, Cukuranovic, Stojnev, Bogdanovic, Rajic, Kocic: "Placental growth factor and placental protein 13 in patients with Balkan endemic nephropathy, a worldwide disease." dans: Renal failure, pp. 1-4, (2015) (PubMed).

Negishi-Koga, Gober, Sumiya, Komatsu, Okamoto, Sawa, Suematsu, Suda, Sato, Takai, Takayanagi: "Immune complexes regulate bone metabolism through FcRγ signalling." dans: Nature communications, Vol. 6, pp. 6637, (2015) (PubMed).

Crotti, Dharmapatni, Alias, Zannettino, Smith, Haynes: "The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints." dans: Arthritis research & therapy, Vol. 14, Issue 6, pp. R245, (2014) (PubMed).

Goettsch, Kliemt, Sinningen, von Bergen, Hofbauer, Kalkhof: "Quantitative proteomics reveals novel functions of osteoclast-associated receptor in STAT signaling and cell adhesion in human endothelial cells." dans: Journal of molecular and cellular cardiology, Vol. 53, Issue 6, pp. 829-37, (2012) (PubMed).

Kim, Kim, Lee, Jin, Lee, Fisher, Kook, Kim, Choi, Kim: "Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis." dans: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35209-16, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à OSCAR

osteoclast associated, immunoglobulin-like receptor (OSCAR), osteoclast-associated immunoglobulin-like receptor (LOC748876), osteoclast associated receptor (Oscar), osteoclast associated, immunoglobulin-like receptor (Oscar), mOSCAR, mOSCAR-M1, mOSCAR-M2, mOSCAR-M3, OSCAR, PIgR-3, PIGR3, RGD1559897

Protein level used designations for OSCAR

  • osteoclast associated, immunoglobulin-like receptor
  • osteoclast associated, immunoglobulin-like receptor, isoform 4
  • ocl178
  • osteoclast-associated immunoglobulin-like receptor
  • osteoclast-associated receptor OSCAR
  • osteoclast associated receptor OSCAR-S1
  • osteoclast associated receptor OSCAR-S2
  • poly-Ig receptor 3
  • polymeric immunoglobulin receptor 3
  • osteoclast associated receptor
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