Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Osteoactivin Produits

(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories Osteoactivin en vedette

Osteoactivin Anticorps

High quality antibodies with extensive validation data.

Osteoactivin Kits ELISA

Reliable ELISA kits for a wide range of species.

Osteoactivin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Osteoactivin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (6)
  • (2)
  • (1)
N° du produit ABIN749093
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (6)
N° du produit ABIN1724859
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
N° du produit ABIN523856
Quantité 100 μg
Fiche technique Fiche technique

Osteoactivin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969089
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5564592
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889404
Quantité 96 tests
Fiche technique Fiche technique

Osteoactivin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274753
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274754
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355562
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Osteoactivin

Neal, Boyle, Budge, Safadi, Richardson: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." dans: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).

Arosarena, Barr, Thorpe, Yankey, Tarr, Safadi: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." dans: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).

Oyewumi, Manickavasagam, Novak, Wehrung, Paulic, Moussa, Sondag, Safadi: "Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells." dans: Oncotarget, Vol. 7, Issue 12, pp. 13932-44, (2017) (PubMed).

Arosarena, Dela Cadena, Denny, Bryant, Barr, Thorpe, Safadi: "Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas." dans: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1761-70, (2016) (PubMed).

Frara, Abdelmagid, Tytell, Amin, Popoff, Safadi, Barbe: "Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping." dans: BMC musculoskeletal disorders, Vol. 17, pp. 34, (2016) (PubMed).

Lin, Li, Xing, Hu, Liang, Han, Wang, Hawke, Wang, Zhang, Wei, Ma, Park, Zhou, Zhou, Hu, Zhou, Marks, Liang, Hung, Lin, Yang: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).

Kramer, Wegdam, Donker-Koopman, Ottenhoff, Gaspar, Verhoek, Nelson, Gabriel, Kallemeijn, Boot, Laman, Vissers, Cox, Pavlova, Moran, Aerts, van Eijk: "Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models." dans: FEBS open bio, Vol. 6, Issue 9, pp. 902-13, (2016) (PubMed).

Ruan, Li, Nie, Zhou, Zou: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." dans: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).

Abdelmagid, Sondag, Moussa, Belcher, Yu, Stinnett, Novak, Mbimba, Khol, Hankenson, Malcuit, Safadi: "Mutation in Osteoactivin Promotes Receptor Activator of NF?B Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function." dans: The Journal of biological chemistry, Vol. 290, Issue 33, pp. 20128-46, (2015) (PubMed).

Torres, Linares, Alejandre, Palomino-Morales, Martin, Delgado, Martinez, Perales: "The potential role of the glycoprotein osteoactivin/glycoprotein nonmetastatic melanoma protein B in pancreatic cancer." dans: Pancreas, Vol. 44, Issue 2, pp. 302-10, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à Osteoactivin

glycoprotein nmb (Gpnmb), glycoprotein nmb (GPNMB), glycoprotein (transmembrane) nmb (Gpnmb), glycoprotein nmb L homeolog (gpnmb.L), DC-HIL, Dchil, HGFIN, ipd, NMB

Protein level used designations for Osteoactivin

  • osteoactivin
  • transmembrane glycoprotein NMB
  • glycoprotein NMB
  • glycoprotein nmb-like protein
  • transmembrane glycoprotein HGFIN
  • dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand
  • dendritic cell-associated transmembrane protein
  • iris pigment dispersion
Vous êtes ici:
Blank Blank Blank Blank
Blank Blank Blank Blank
Support technique