PAICS Produits
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Catégories
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories PAICS en vedette
PAICS Anticorps
High quality antibodies with extensive validation data.
PAICS Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PAICS recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (4)
N° du produit
ABIN656869
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7160326
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7237569
Quantité
200 μL
Fiche technique
Fiche technique
PAICS recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6229169
Quantité
96 tests
Fiche technique
Fiche technique
PAICS recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124444
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313911
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2131021
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PAICS
: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." dans: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).: "Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders." dans: Molecular genetics and metabolism, Vol. 108, Issue 3, pp. 178-89, (2013) (PubMed).
: "Transiently transfected purine biosynthetic enzymes form stress bodies." dans: PLoS ONE, Vol. 8, Issue 2, pp. e56203, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (PAICS), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (paics), multifunctional protein ADE2 (LOC551966), multifunctional protein ADE2 (Tsp_02239a), multifunctional protein ADE2 (Tsp_02239), phosphoribosylaminoimidazole carboxylase (CNE02500), phosphoribosylaminoimidazole carboxylase (purC/E), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (Paics), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog (paics.2.L), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), 2610511I09Rik, ADE2, ade2, ADE2H1, Ade2h1, AIRC, Airc, airc, AS, cb293, DDBDRAFT_0218550, DDBDRAFT_0230088, DDB_0218550, DDB_0230088, GB14262, paics, PAIS, pais, sb:cb293, wu:fa28a05Protein level used designations for PAICS
- multifunctional protein ADE2
- phosphoribosylaminoimidazole carboxylase
- phosphoribosylaminoimidazolesuccinocarboxamide synthase
- AIR carboxylase domain
- AIR carboxylase
- SAICAR synthetase
- multifunctional protein ADE2H1
- phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase
- Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase
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