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PAK3 Produits

(PAK3)

Catégories

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories PAK3 en vedette

PAK3 Anticorps

High quality antibodies with extensive validation data.

PAK3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PAK3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
N° du produit ABIN518612
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (4)
N° du produit ABIN5611206
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (5)
N° du produit ABIN3028914
Quantité 0.4 mL
Fiche technique Fiche technique

PAK3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380787
Quantité 2 x 96 tests
Fiche technique Fiche technique

PAK3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313925
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7317075
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN5509220
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PAK3

Wang, Gratzke, Tamalunas, Wiemer, Ciotkowska, Rutz, Waidelich, Strittmatter, Liu, Stief, Hennenberg: "P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0153312, (2016) (PubMed).

Valente, Turacchio, Mariggiò, Pagliuso, Gaibisso, Di Tullio, Santoro, Formiggini, Spanò, Piccini, Polishchuk, Colanzi, Luini, Corda: "A 14-3-3? dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII? to regulate post-Golgi carrier formation." dans: Nature cell biology, Vol. 14, Issue 4, pp. 343-54, (2012) (PubMed).

Kitano, Schwarz, Nickel, Pääbo: "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees." dans: Molecular biology and evolution, Vol. 20, Issue 8, pp. 1281-9, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à PAK3

p21 (RAC1) activated kinase 3 (PAK3), p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3), p21 (RAC1) activated kinase 3 (Pak3), p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog (pak3.L), beta-PAK, bPAK, bpak, CDKN1A, cdkn1a, hPAK3, MRX30, mrx30, MRX47, mrx47, OPHN3, ophn3, PAK-3, pak3, pak3-A, PAK3beta, pak3beta, Pak65alpha, Pak65beta, Stk4, XPak3

Protein level used designations for PAK3

  • PAK-3
  • beta-PAK
  • oligophrenin-3
  • p21 (CDKN1A)-activated kinase 3
  • p21-activated kinase 3
  • serine/threonine-protein kinase PAK 3
  • CDC42/RAC effector kinase PAK-B
  • p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related)
  • p65-PAK
  • PAK3a protein
  • PAK3d protein
  • serine/threonine protein kinase (p21-activated kinase 3)
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