PARL Produits
(Presenilin Associated, Rhomboid-Like (PARL))
Catégories
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories PARL en vedette
PARL Anticorps
High quality antibodies with extensive validation data.
PARL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PARL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (5)
N° du produit
ABIN2782038
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN634971
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7164273
Quantité
100 μL
Fiche technique
Fiche technique
PARL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314017
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314016
Quantité
25 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PARL
: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." dans: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).
: "Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling." dans: Cell, Vol. 126, Issue 1, pp. 163-75, (2006) (PubMed).
: "Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18562-7, (2006) (PubMed).
: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." dans: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).
: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." dans: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PARL
presenilin associated rhomboid like (PARL), presenilin associated, rhomboid-like (Parl), presenilin associated rhomboid like (Parl), presenilin associated, rhomboid-like a (parla), D16Ertd607e, parl, PRO2207, PSARL, Psarl, PSARL1, PSENIP2, RHBDS1, zgc:112986Protein level used designations for PARL
- mitochondrial intramembrane cleaving protease PARL
- mitochondrial intramembrane-cleaving protease PARL
- presenilins-associated rhomboid-like protein, mitochondrial
- rhomboid 7 homolog 1
- presenilin associated, rhomboid-like isoform 1 preproprotein
- presenilin associated, rhomboid-like preproprotein
- parlb
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