Patched 1 Produits
(Patched 1 (PTCH1))
Catégories
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008].
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Catégories Patched 1 en vedette
Patched 1 Anticorps
High quality antibodies with extensive validation data.
Patched 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Patched 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Patched 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC, IF
Validations
- (2)
- (7)
N° du produit
ABIN185521
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
N° du produit
ABIN7255007
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
N° du produit
ABIN3015343
Quantité
100 μL
Fiche technique
Fiche technique
Patched 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958422
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381402
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Chicken
Analytical Method
Validations
N° du produit
ABIN1152106
Quantité
96 tests
Fiche technique
Fiche technique
Patched 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316702
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316700
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505336
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Patched 1
: "Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo." dans: International journal of cancer, Vol. 143, Issue 1, pp. 199-211, (2019) (PubMed).: "Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling." dans: Experimental cell research, Vol. 371, Issue 2, pp. 417-425, (2018) (PubMed).
: "Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment." dans: Biology of reproduction, Vol. 96, Issue 2, pp. 313-326, (2017) (PubMed).
: "Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway." dans: Life sciences, Vol. 191, pp. 82-89, (2017) (PubMed).
: "Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate." dans: PLoS genetics, Vol. 12, Issue 10, pp. e1006352, (2016) (PubMed).
: "Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma." dans: Molecular cancer therapeutics, Vol. 15, Issue 5, pp. 1095-105, (2016) (PubMed).
: "Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen." dans: Experimental neurology, Vol. 271, pp. 493-505, (2015) (PubMed).
: "Developmental Status: Impact of Short-Term Ischemia on Follicular Survival of Whole Ovarian Transplantation in a Rabbit Model." dans: PLoS ONE, Vol. 10, Issue 8, pp. e0135049, (2015) (PubMed).
: "Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling." dans: Journal of neuro-oncology, Vol. 119, Issue 2, pp. 243-51, (2014) (PubMed).
: "High expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma." dans: OncoTargets and therapy, Vol. 7, pp. 79-86, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à Patched 1
patched 1 (PTCH1), patched 1 (ptch1), patched 1 (Ptch1), patched 1 L homeolog (ptch1.L), Protein patched homolog 1 (ptc-1), A230106A15Rik, BCNS, HPE7, lep, mes, NBCCS, patched, patched1, PTC, Ptc, Ptc-1, PTC1, ptc1, Ptc1, ptc2, PTCH, Ptch, Ptch2, PTCH11, XPtc1Protein level used designations for Patched 1
- PTCH protein +12b
- PTCH protein +4'
- PTCH protein -10
- PTCH protein -3,4,5
- protein patched homolog 1
- leprechaun
- patched 2
- patched homolog 2
- patched homolog 1
- patched-1
- patched 1
- patched-like
- protein patched homolog 1-like
- Patched 1
- Ptch1 protein +12b
- mesenchymal dysplasia
- PTC1
- patched protein
- patched-like protein
- LOW QUALITY PROTEIN: protein patched homolog 1
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