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P2RY12 Produits

(Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Catégories

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories P2RY12 en vedette

P2RY12 Anticorps

High quality antibodies with extensive validation data.

P2RY12 Kits ELISA

Reliable ELISA kits for a wide range of species.

P2RY12 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

P2RY12 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
N° du produit ABIN5611346
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc)
Validations
  • (4)
N° du produit ABIN1387659
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7075321
Quantité 100 μL
Fiche technique Fiche technique

P2RY12 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969784
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958996
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511471
Quantité 96 tests
Fiche technique Fiche technique

P2RY12 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408405
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Mammalian Cells
Validations
N° du produit ABIN7538496
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3118050
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits P2RY12

Lim, Hainsworth, Mohan, Chaurasia: "Characterization of a functionally active primary microglial cell culture from the pig retina." dans: Experimental eye research, Vol. 185, pp. 107670, (2019) (PubMed).

Walker, Lue, Beach, Tooyama: "Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin." dans: Cells, Vol. 8, Issue 7, (2019) (PubMed).

Morin-Brureau, Milior, Royer, Chali, LeDuigou, Savary, Blugeon, Jourdren, Akbar, Dupont, Navarro, Baulac, Bielle, Mathon, Clemenceau, Miles: "Microglial phenotypes in the human epileptic temporal lobe." dans: Brain : a journal of neurology, Vol. 141, Issue 12, pp. 3343-3360, (2018) (PubMed).

Garcia-Mesa, Jay, Checkley, Luttge, Dobrowolski, Valadkhan, Landreth, Karn, Alvarez-Carbonell: "Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system." dans: Journal of neurovirology, Vol. 23, Issue 1, pp. 47-66, (2016) (PubMed).

Bornø, Ploug, Bune, Rosenmeier, Thaning: "Purinergic receptors expressed in human skeletal muscle fibres." dans: Purinergic signalling, Vol. 8, Issue 2, pp. 255-64, (2012) (PubMed).

Neves, Radke, Weller: "Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules." dans: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 477-82, (2010) (PubMed).

Savi, Zachayus, Delesque-Touchard, Labouret, Hervé, Uzabiaga, Pereillo, Culouscou, Bono, Ferrara, Herbert: "The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 29, pp. 11069-74, (2006) (PubMed).

Abbracchio, Burnstock: "Purinoceptors: are there families of P2X and P2Y purinoceptors?" dans: Pharmacology & therapeutics, Vol. 64, Issue 3, pp. 445-75, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à P2RY12

purinergic receptor P2Y, G-protein coupled 12 (P2ry12), purinergic receptor P2Y12 (P2RY12), purinergic receptor P2Y12 (P2ry12), 2900079B22Rik, 4921504D23Rik, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, P2y12, SP1999

Protein level used designations for P2RY12

  • P2Y purinoceptor 12
  • ADP-glucose receptor
  • G-protein coupled receptor SP1999
  • Gi-coupled ADP receptor HORK3
  • P2Y12 platelet ADP receptor
  • purinergic receptor P2RY12
  • putative G-protein coupled receptor
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