PBX1 Produits
(Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
Catégories
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Catégories PBX1 en vedette
PBX1 Anticorps
High quality antibodies with extensive validation data.
PBX1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PBX1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PBX1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
- (5)
N° du produit
ABIN562114
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (3)
N° du produit
ABIN7164137
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN571168
Quantité
100 μg
Fiche technique
Fiche technique
PBX1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1149119
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1149118
Quantité
96 tests
Fiche technique
Fiche technique
PBX1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124544
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314106
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN5954421
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PBX1
: "The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1." dans: Cell reports, Vol. 14, Issue 5, pp. 1156-1168, (2016) (PubMed).: "Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion." dans: Nature communications, Vol. 6, pp. 10044, (2015) (PubMed).
: "Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 8, pp. 1960-71, (2013) (PubMed).
: "Cooperative transcriptional activation by Klf4, Meis2, and Pbx1." dans: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3723-33, (2011) (PubMed).
: "PBX1 genomic pioneer function drives ER? signaling underlying progression in breast cancer." dans: PLoS genetics, Vol. 7, Issue 11, pp. e1002368, (2011) (PubMed).
: "Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation." dans: Human molecular genetics, Vol. 18, Issue 4, pp. 679-87, (2009) (PubMed).
: "Gfi1 integrates progenitor versus granulocytic transcriptional programming." dans: Blood, Vol. 113, Issue 22, pp. 5466-75, (2009) (PubMed).
: "Evaluating the association of common PBX1 variants with type 2 diabetes." dans: BMC medical genetics, Vol. 9, pp. 14, (2008) (PubMed).
: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." dans: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).
: "Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth." dans: The American journal of pathology, Vol. 170, Issue 1, pp. 152-9, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à PBX1
PBX homeobox 1 (PBX1), pre-B-cell leukemia homeobox 1a (pbx1a), pre B cell leukemia homeobox 1 (Pbx1), PBX homeobox 1 (Pbx1), pre-B-cell leukemia homeobox 1 S homeolog (pbx1.S), 2310056B04Rik, AI848790, AU015730, D230003C07Rik, fi29e01, Pbx-1, Pbx1a, PBX1A, pbx1b, Pbx1b, wu:fi29e01, Xpbx1, Xpbx1b, zgc:55265Protein level used designations for PBX1
- homeobox protein PBX1
- homeobox protein PRL
- pre-B-cell leukemia transcription factor 1
- pre-B-cell leukemia transcription factor 1b
- pre B-cell leukemia transcription factor 1
- Homeobox protein pbx1
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