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PCDHGB2 Produits

(Protocadherin gamma Subfamily B, 2 (PCDHGB2))
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].

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Catégories PCDHGB2 en vedette

PCDHGB2 Anticorps

High quality antibodies with extensive validation data.

PCDHGB2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PCDHGB2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN565980
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN1539095
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN565979
Quantité 50 μL
Fiche technique Fiche technique

PCDHGB2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314264
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314266
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2728396
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PCDHGB2

Lobas, Helsper, Vernon, Schreiner, Zhang, Holtzman, Thedens, Weiner: "Molecular heterogeneity in the choroid plexus epithelium: the 22-member ?-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation." dans: Journal of neurochemistry, Vol. 120, Issue 6, pp. 913-27, (2012) (PubMed).

Prasad, Weiner: "Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the ?-Protocadherins." dans: Frontiers in molecular neuroscience, Vol. 4, pp. 54, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à PCDHGB2

protocadherin gamma subfamily B, 2 (PCDHGB2), protocadherin gamma subfamily B, 2 (Pcdhgb2), PCDH-GAMMA-B2

Protein level used designations for PCDHGB2

  • protocadherin gamma-B2
  • 3' RACE product
  • protocadherin gamma B2
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