The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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polycomb group ring finger 6 (PCGF6), polycomb group ring finger 6 (pcgf6), polycomb group ring finger 6 (Pcgf6), 4933407A11Rik, AI604840, im:7144322, MBLR, RNF134, Rnf134, si:ch211-67n3.7