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PCM1 Produits

(Pericentriolar Material 1 (PCM1))
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. [provided by RefSeq, Sep 2010].

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Catégories PCM1 en vedette

PCM1 Anticorps

High quality antibodies with extensive validation data.

PCM1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PCM1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PCM1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IF, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN391696
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN391695
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
N° du produit ABIN7162885
Quantité 100 μL
Fiche technique Fiche technique

PCM1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1147379
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1147378
Quantité 96 tests
Fiche technique Fiche technique

PCM1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314322
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422808
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418656
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PCM1

Aziz, Sieben, Jeganathan, Hamada, Davies, Velasco, Rahman, Katzmann, van Deursen: "Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression." dans: The Journal of clinical investigation, Vol. 128, Issue 8, pp. 3517-3534, (2018) (PubMed).

Shiratsuchi, Takaoka, Ashikawa, Hamada, Kitagawa: "RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity." dans: The EMBO journal, Vol. 34, Issue 1, pp. 97-114, (2015) (PubMed).

Nührenberg, Hammann, Schnick, Preißl, Witten, Stoll, Gilsbach, Neumann, Hein: "Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0131019, (2015) (PubMed).

Wei, Serpooshan, Hurtado, Diez-Cuñado, Zhao, Maruyama, Zhu, Fajardo, Noseda, Nakamura, Tian, Liu, Wang, Matsuura, Bushway, Cai, Savchenko, Mahmoudi, Schneider, van den Hoff, Butte, Yang, Walsh, Zhou et al.: "Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. ..." dans: Nature, Vol. 525, Issue 7570, pp. 479-85, (2015) (PubMed).

Fang, Zhang, Yin, Zheng, Bi, Yuan: "Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion." dans: Journal of cell science, Vol. 127, Issue Pt 8, pp. 1631-9, (2014) (PubMed).

Gilsbach, Preissl, Grüning, Schnick, Burger, Benes, Würch, Bönisch, Günther, Backofen, Fleischmann, Schübeler, Hein: "Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease." dans: Nature communications, Vol. 5, pp. 5288, (2014) (PubMed).

Chakravarthy, Ménard, Brown, Hewitt, Atkinson, Whitfield: "A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers." dans: Journal of neurochemistry, Vol. 126, Issue 3, pp. 415-24, (2013) (PubMed).

Zhang, Seo, Bhattarai, Bugge, Searby, Zhang, Drack, Stone, Sheffield: "BBS mutations modify phenotypic expression of CEP290-related ciliopathies." dans: Human molecular genetics, Vol. 23, Issue 1, pp. 40-51, (2013) (PubMed).

Humbert, Weihbrecht, Searby, Li, Pope, Sheffield, Seo: "ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 48, pp. 19691-6, (2012) (PubMed).

Akimov, Rigbolt, Nielsen, Blagoev: "Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics." dans: Molecular bioSystems, Vol. 7, Issue 12, pp. 3223-33, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à PCM1

pericentriolar material 1 (pcm1), pericentriolar material 1 (PCM1), pericentriolar material 1 (Pcm1), pericentriolar material 1 L homeolog (pcm1.L), 2600002H09Rik, 9430077F19Rik, C030044G17Rik, pcm-1, PCM-1, PCM1, ptc4, PTC4, wu:fb30g01, wu:fb94e03, wu:fe14f07

Protein level used designations for PCM1

  • pericentriolar material 1
  • pericentriolar material 1 protein-like
  • Pericentriolar material 1 protein-like
  • PCM-1
  • hPCM-1
  • pericentriolar material 1 protein
  • pericentriolar material 1, PCM1
  • mPCM-1
  • pericentriolar material gene 1
  • pericentriolar material-1
  • xPCM-1
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