PCSK1 Produits
(Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
Catégories
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010].
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Catégories PCSK1 en vedette
PCSK1 Anticorps
High quality antibodies with extensive validation data.
PCSK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PCSK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PCSK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (7)
N° du produit
ABIN7435748
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7443446
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (8)
N° du produit
ABIN562137
Quantité
100 μg
Fiche technique
Fiche technique
PCSK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958849
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958850
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1571753
Quantité
96 tests
Fiche technique
Fiche technique
PCSK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314348
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7406851
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN1989721
Quantité
25 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PCSK1
: "ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling." dans: Cell and tissue research, Vol. 352, Issue 2, pp. 413-25, (2013) (PubMed).: "Functional melanocortin-2 receptors are expressed by mouse aorta-derived mesenchymal progenitor cells." dans: Molecular and cellular endocrinology, Vol. 355, Issue 1, pp. 60-70, (2012) (PubMed).
: "Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity." dans: Molecular genetics and metabolism, Vol. 104, Issue 4, pp. 682-7, (2011) (PubMed).
: "Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency." dans: The Journal of clinical investigation, Vol. 112, Issue 10, pp. 1550-60, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à PCSK1
proprotein convertase subtilisin/kexin type 1 (PCSK1), proprotein convertase subtilisin/kexin type 1 (Pcsk1), proprotein convertase subtilisin/kexin type 1 (pcsk1), prohormone convertase 1 (PC1B), BDP, BMIQ12, Nec-1, NEC1, Nec1, PC1, PC1/3, PC3, Phpp-1, SPC3Protein level used designations for PCSK1
- NEC 1
- neuroendocrine convertase 1
- prohormone convertase 1
- prohormone convertase 3
- furin homolog
- prohormone convertase 1/3
- propeptide-processing protease
- proprotein convertase 1
- Protein convertase subtilisin / kexin type I
- Protein convertase subtilisin / kexin, type I
- prohormone convertase
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